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• W2151404452 endingPage "100" @default.
• W2151404452 startingPage "91" @default.
• W2151404452 abstract "Histone deacetylase (HDAC) inhibitors are currently used in the study of epigenetics and have potential in clinical cancer therapy. A novel and potent HDAC inhibitor, depsipeptide, also known as FK228 or FR901228, is highly efficient in inhibiting the activity of HDACs even at nanomolar concentrations. Depsipeptide has a unique structure that is distinct from most of the other HDACs, and it thus exhibits diverse pharmacologic functions. In addition, depsipeptide has a metabolic activation pathway, which affects many intracellular processes. However, the specific features of this pathway are as yet not completely worked out. In this article, we will focus on the uniqueness of this molecules specific structure, the relationship of this structure to its putative metabolic activation pathway, and specifically review its newly discovered biological functions and clinical applications. Keywords: Histone deacetylase, HDAC inhibitor, depsipeptide, SAHA, TSA" @default.
• W2151404452 created "2016-06-24" @default.
• W2151404452 creator A5062451164 @default.
• W2151404452 creator A5084743296 @default.
• W2151404452 date "2009-02-01" @default.
• W2151404452 modified "2023-10-17" @default.
• W2151404452 title "The Changing Face of HDAC Inhibitor Depsipeptide" @default.
• W2151404452 cites W122083802 @default.
• W2151404452 cites W1546653512 @default.
• W2151404452 cites W1587031596 @default.
• W2151404452 cites W160911776 @default.
• W2151404452 cites W186738419 @default.
• W2151404452 cites W1966138340 @default.
• W2151404452 cites W1968006317 @default.
• W2151404452 cites W1968489542 @default.
• W2151404452 cites W1971621147 @default.
• W2151404452 cites W1971966311 @default.
• W2151404452 cites W1972149587 @default.
• W2151404452 cites W1972378799 @default.
• W2151404452 cites W1973788312 @default.
• W2151404452 cites W1974836748 @default.
• W2151404452 cites W1976873804 @default.
• W2151404452 cites W1980271365 @default.
• W2151404452 cites W1981259598 @default.
• W2151404452 cites W1982545065 @default.
• W2151404452 cites W1987949891 @default.
• W2151404452 cites W1988220701 @default.
• W2151404452 cites W1989184574 @default.
• W2151404452 cites W1991494214 @default.
• W2151404452 cites W1992321786 @default.
• W2151404452 cites W1995902306 @default.
• W2151404452 cites W2002698073 @default.
• W2151404452 cites W2002705413 @default.
• W2151404452 cites W2009121506 @default.
• W2151404452 cites W2019024225 @default.
• W2151404452 cites W2026666255 @default.
• W2151404452 cites W2027072436 @default.
• W2151404452 cites W2028787191 @default.
• W2151404452 cites W2032232569 @default.
• W2151404452 cites W2033747485 @default.
• W2151404452 cites W2034059961 @default.
• W2151404452 cites W2034562270 @default.
• W2151404452 cites W2035188342 @default.
• W2151404452 cites W2035209422 @default.
• W2151404452 cites W2039013619 @default.
• W2151404452 cites W2043985316 @default.
• W2151404452 cites W2044303805 @default.
• W2151404452 cites W2045552152 @default.
• W2151404452 cites W2050420673 @default.
• W2151404452 cites W2057087535 @default.
• W2151404452 cites W2057355492 @default.
• W2151404452 cites W2060733408 @default.
• W2151404452 cites W2060869819 @default.
• W2151404452 cites W2063827408 @default.
• W2151404452 cites W2068351024 @default.
• W2151404452 cites W2069301193 @default.
• W2151404452 cites W2070437897 @default.
• W2151404452 cites W2072119701 @default.
• W2151404452 cites W2076446466 @default.
• W2151404452 cites W2083627679 @default.
• W2151404452 cites W2090094306 @default.
• W2151404452 cites W2092722802 @default.
• W2151404452 cites W2093507272 @default.
• W2151404452 cites W2095899172 @default.
• W2151404452 cites W2100230735 @default.
• W2151404452 cites W2102723918 @default.
• W2151404452 cites W2106061659 @default.
• W2151404452 cites W2106357158 @default.
• W2151404452 cites W2106715610 @default.
• W2151404452 cites W2106888057 @default.
• W2151404452 cites W2108230631 @default.
• W2151404452 cites W2111178066 @default.
• W2151404452 cites W2111447146 @default.
• W2151404452 cites W2113144329 @default.
• W2151404452 cites W2118535812 @default.
• W2151404452 cites W2121296685 @default.
• W2151404452 cites W2121417064 @default.
• W2151404452 cites W2122107343 @default.
• W2151404452 cites W2122869974 @default.
• W2151404452 cites W2123744235 @default.
• W2151404452 cites W2123927456 @default.
• W2151404452 cites W2130227833 @default.
• W2151404452 cites W2131317966 @default.
• W2151404452 cites W2131331729 @default.
• W2151404452 cites W2133127743 @default.
• W2151404452 cites W2133888235 @default.
• W2151404452 cites W2133918562 @default.
• W2151404452 cites W2135085078 @default.
• W2151404452 cites W2136492640 @default.
• W2151404452 cites W2137071178 @default.
• W2151404452 cites W2141410747 @default.
• W2151404452 cites W2142837955 @default.
• W2151404452 cites W2143658931 @default.
• W2151404452 cites W2144266634 @default.
• W2151404452 cites W2144792857 @default.
• W2151404452 cites W2145036053 @default.
• W2151404452 cites W2147220700 @default.
• W2151404452 cites W2147723796 @default.

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