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• W2151405455 endingPage "55" @default.
• W2151405455 startingPage "49" @default.
• W2151405455 abstract "Mutants of Escherichia coli K-12 resistant to either the threonine analog DL-alpha-amino-beta-hydroxyvaleric acid or the leucine analog 5',5',5'-trifluoro-DL-leucine were isolated. One DL-alpha-amino-beta-hydroxyvaleric acid-resistant mutant strain, designated SP572, constitutively expressed the thr and ilv operons. The mutant allele, avr-16, was localized between trpR and the thr operon at min 0. The wildtype allele of avr-16, designated ileR, is trans dominant. One 5',5',5'-trifluoro-DL-leucine-resistant mutant strain, designated FLR9, expressed the leu and ilv operons constitutively. The mutant allele, flr-9, is linked to entA at min 13. The constitutive expression of the thr, leu, and ilv operons in mutants avr-16 and flr-9 was partly reversed in cells harboring a plasmid, which leads to elevated levels of the trpR gene product, the Trp aporepressor protein. Operator-like sequences situated upstream from the transcription startpoints of the thr, leu, and ilv operons are plausible candidates for targets of systems of repressor-operator control functioning in parallel with attenuation." @default.
• W2151405455 created "2016-06-24" @default.
• W2151405455 creator A5032297688 @default.
• W2151405455 creator A5042900625 @default.
• W2151405455 date "1983-07-01" @default.
• W2151405455 modified "2023-10-18" @default.
• W2151405455 title "Evidence that repression mechanisms can exert control over the thr, leu, and ilv operons of Escherichia coli K-12" @default.
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• W2151405455 doi "https://doi.org/10.1128/jb.155.1.49-55.1983" @default.
• W2151405455 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/217650" @default.
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• W2151405455 hasPublicationYear "1983" @default.
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