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• W2151421236 abstract "performed a primary task. The primary tasks were designed to induce changes in slow cortical potentials (SCP) such as P300, contingent negative variation (CNV), and postimperative negative variation (PINV). Brief auditory stimuli were presented before, during or after the primary task. The interactions between the two types of event-related potentials, SCP and the probe-evoked N 1/P2, served to further explore the nature of SCP, particularly in its relation to excitability in cortical neuronal networks. The functional state indicated by SCP was also probed in patients with a chronic schizophrenic disorder, who are known to exhibit deviant SCP. Increased amplitudes of the probe-evoked vertex potential (N1/P2) and faster motor responses to probes during the CNV, and reduced N 1/P2-omplitudes and delayed motor responses during positive waves (P300) support the hypothesis that anticipatory cortical negativity indicates excitation in cortical neuronal networks while positive-going waves may indicate widespread cortical suppression (with focused islands of cortical excitability). Increased amplitudes of the N 1/P2 during the CNV but not during the PINV suggest a different functional significance of these two negative-going slow waves. Although schizophrenic patients displayed different amplitudes and scalp distribution, particularly of the PINV, suggesting a deviant spatia-temporal regulation of cortical excitability, the functional relation between SCP and probe-related activity was similar in schizophrenic patients and control subjects." @default.
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• W2151421236 date "1997-01-01" @default.
• W2151421236 modified "2023-09-23" @default.
• W2151421236 title "The chronometrics of cortical excitation as explored with auditory probes" @default.
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