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• W2151428384 abstract "Isomeric oxo-bridged analogs of aza-trishomocubane sigma (σ) receptor ligands were synthesized and shown to display a reduced affinity for the σ receptor. In the case of phenethyl derivative 4, there was a concomitant introduction of high-affinity for the α2C adrenergic receptor, and moderate affinity for the dopamine transporter. Molecular modeling was undertaken to rationalize these results." @default.
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• W2151428384 date "2010-01-01" @default.
• W2151428384 modified "2023-10-18" @default.
• W2151428384 title "Oxo-bridged isomers of aza-trishomocubane sigma (σ) receptor ligands: Synthesis, in vitro binding, and molecular modeling" @default.
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• W2151428384 doi "https://doi.org/10.1016/j.bmcl.2009.11.019" @default.
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