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• W2151446658 abstract "Current international recommendations advise aggressive treatment of relative hypercholesterolemia despite an incomplete understanding of any neurobehavioral effects of low or lowered serum cholesterol.The objective was to examine the relation between serum cholesterol concentrations and performance in immediate memory, visuomotor speed, and coding speed tests.The participants were 4110 adults aged 20-59 y who completed a set of neurobehavioral tests and had blood specimens collected as a part of the third National Health and Nutrition Examination Survey, 1988-1994.After adjustment for sociodemographic variables, serum trace elements and vitamins, dietary energy intake, and risk factors for cardiovascular disease, we found inverse linear associations of serum total cholesterol and non-HDL cholesterol with visuomotor speed in men. The least-squares mean (+/- SE) visuomotor speeds were 231.6 +/- 2.6, 224.0 +/- 2.2, and 218.9 +/- 2.5 ms, respectively, for men with serum total cholesterol concentrations below the 25th, between the 25th and the 75th, and at or above the 75th percentile (P for trend < 0.001) and were 231.7 +/- 2.7, 225.8 +/- 2.4, and 214.1 +/- 2.3 ms, respectively, for men with a non-HDL-cholesterol concentration below the 25th, between the 25th and the 75th, and at or above the 75th percentile (P for trend < 0.001). No significant associations were observed between memory or coding speed and the selected serum cholesterol measures in men, and the scores of the 3 neurobehavioral tests were unrelated to serum cholesterol in women.Low serum total cholesterol and non-HDL cholesterol are associated with slow visuomotor speed in young and middle-aged men." @default.
• W2151446658 created "2016-06-24" @default.
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• W2151446658 date "2004-08-01" @default.
• W2151446658 modified "2023-10-16" @default.
• W2151446658 title "Serum cholesterol concentrations are associated with visuomotor speed in men: findings from the third National Health and Nutrition Examination Survey, 1988–1994" @default.
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• W2151446658 doi "https://doi.org/10.1093/ajcn/80.2.291" @default.
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