FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2151546856> ?p ?o ?g. }

• W2151546856 endingPage "e24" @default.
• W2151546856 startingPage "e24" @default.
• W2151546856 abstract "PurposeWe have designed a novel biodegradable, aligned nanofibrous scaffold for augmenting the repair of meniscal tears historically considered irreparable. As a first step in this endeavor, scaffold fixation to meniscal tissue was quantified by comparing suture pull-out from scaffolds and fixation strength to the native tissue.MethodsTwo suture types: monofilament (Prolene) and braided (Ticron) of equal diameter; and, two knots: horizontal mattress (HM) and -caprolacone fiber aligned and ε vertical mattress (VM) were investigated. Poly- non-aligned meshes were produced via electrospinning. Tensile testing to failure of the suture was carried out at 0.1% elongation/second. An “apparent” Young’s modulus was calculated from the stress-strain profile and scaffold geometry. Subsequently, circumferentially aligned bovine meniscal strips were sutured parallel to aligned scaffolds using single or double VM or HM with Ticron suture.ResultsThe apparent Young’s modulus was 15 MPa for the aligned group sutured with a Ticron HM compared to 5 MPa for the same scaffold sutured with a Prolene HM (Figure 1, left, p<0.01). There was no significant difference in the tensile strength between HM and VM knots. When sutured to native meniscus, double knots provided slightly stronger fixation (Figure 1, right).ConclusionThis study confirms that aligned scaffolds have superior tensile properties compared to non-aligned scaffolds and that a braided Ticron suture material provides a more stable fixation. Moreover, increasing number of VM Ticron knots were shown to improve the fixation strength of fiber-aligned scaffolds to the native tissue. PurposeWe have designed a novel biodegradable, aligned nanofibrous scaffold for augmenting the repair of meniscal tears historically considered irreparable. As a first step in this endeavor, scaffold fixation to meniscal tissue was quantified by comparing suture pull-out from scaffolds and fixation strength to the native tissue. We have designed a novel biodegradable, aligned nanofibrous scaffold for augmenting the repair of meniscal tears historically considered irreparable. As a first step in this endeavor, scaffold fixation to meniscal tissue was quantified by comparing suture pull-out from scaffolds and fixation strength to the native tissue. MethodsTwo suture types: monofilament (Prolene) and braided (Ticron) of equal diameter; and, two knots: horizontal mattress (HM) and -caprolacone fiber aligned and ε vertical mattress (VM) were investigated. Poly- non-aligned meshes were produced via electrospinning. Tensile testing to failure of the suture was carried out at 0.1% elongation/second. An “apparent” Young’s modulus was calculated from the stress-strain profile and scaffold geometry. Subsequently, circumferentially aligned bovine meniscal strips were sutured parallel to aligned scaffolds using single or double VM or HM with Ticron suture. Two suture types: monofilament (Prolene) and braided (Ticron) of equal diameter; and, two knots: horizontal mattress (HM) and -caprolacone fiber aligned and ε vertical mattress (VM) were investigated. Poly- non-aligned meshes were produced via electrospinning. Tensile testing to failure of the suture was carried out at 0.1% elongation/second. An “apparent” Young’s modulus was calculated from the stress-strain profile and scaffold geometry. Subsequently, circumferentially aligned bovine meniscal strips were sutured parallel to aligned scaffolds using single or double VM or HM with Ticron suture. ResultsThe apparent Young’s modulus was 15 MPa for the aligned group sutured with a Ticron HM compared to 5 MPa for the same scaffold sutured with a Prolene HM (Figure 1, left, p<0.01). There was no significant difference in the tensile strength between HM and VM knots. When sutured to native meniscus, double knots provided slightly stronger fixation (Figure 1, right). The apparent Young’s modulus was 15 MPa for the aligned group sutured with a Ticron HM compared to 5 MPa for the same scaffold sutured with a Prolene HM (Figure 1, left, p<0.01). There was no significant difference in the tensile strength between HM and VM knots. When sutured to native meniscus, double knots provided slightly stronger fixation (Figure 1, right). ConclusionThis study confirms that aligned scaffolds have superior tensile properties compared to non-aligned scaffolds and that a braided Ticron suture material provides a more stable fixation. Moreover, increasing number of VM Ticron knots were shown to improve the fixation strength of fiber-aligned scaffolds to the native tissue. This study confirms that aligned scaffolds have superior tensile properties compared to non-aligned scaffolds and that a braided Ticron suture material provides a more stable fixation. Moreover, increasing number of VM Ticron knots were shown to improve the fixation strength of fiber-aligned scaffolds to the native tissue." @default.
• W2151546856 created "2016-06-24" @default.
• W2151546856 creator A5015297374 @default.
• W2151546856 creator A5016850109 @default.
• W2151546856 creator A5030866046 @default.
• W2151546856 creator A5037559298 @default.
• W2151546856 creator A5049365881 @default.
• W2151546856 creator A5057499766 @default.
• W2151546856 date "2006-06-01" @default.
• W2151546856 modified "2023-09-26" @default.
• W2151546856 title "Suture Fixation of Biodegradable Nanofibrous Poly-Caprolactone Scaffolds to Bovine Meniscus: A Novel Approach to Repairing Meniscal Tears (SS-48)" @default.
• W2151546856 doi "https://doi.org/10.1016/j.arthro.2006.04.050" @default.
• W2151546856 hasPublicationYear "2006" @default.
• W2151546856 type Work @default.
• W2151546856 sameAs 2151546856 @default.
• W2151546856 citedByCount "0" @default.
• W2151546856 crossrefType "journal-article" @default.
• W2151546856 hasAuthorship W2151546856A5015297374 @default.
• W2151546856 hasAuthorship W2151546856A5016850109 @default.
• W2151546856 hasAuthorship W2151546856A5030866046 @default.
• W2151546856 hasAuthorship W2151546856A5037559298 @default.
• W2151546856 hasAuthorship W2151546856A5049365881 @default.
• W2151546856 hasAuthorship W2151546856A5057499766 @default.
• W2151546856 hasConcept C105702510 @default.
• W2151546856 hasConcept C112950240 @default.
• W2151546856 hasConcept C136229726 @default.
• W2151546856 hasConcept C141071460 @default.
• W2151546856 hasConcept C142724271 @default.
• W2151546856 hasConcept C146249460 @default.
• W2151546856 hasConcept C159985019 @default.
• W2151546856 hasConcept C192562407 @default.
• W2151546856 hasConcept C204787440 @default.
• W2151546856 hasConcept C2776164576 @default.
• W2151546856 hasConcept C2776454340 @default.
• W2151546856 hasConcept C2777327002 @default.
• W2151546856 hasConcept C2779980959 @default.
• W2151546856 hasConcept C2780423099 @default.
• W2151546856 hasConcept C2908647359 @default.
• W2151546856 hasConcept C71924100 @default.
• W2151546856 hasConcept C89429830 @default.
• W2151546856 hasConcept C99454951 @default.
• W2151546856 hasConceptScore W2151546856C105702510 @default.
• W2151546856 hasConceptScore W2151546856C112950240 @default.
• W2151546856 hasConceptScore W2151546856C136229726 @default.
• W2151546856 hasConceptScore W2151546856C141071460 @default.
• W2151546856 hasConceptScore W2151546856C142724271 @default.
• W2151546856 hasConceptScore W2151546856C146249460 @default.
• W2151546856 hasConceptScore W2151546856C159985019 @default.
• W2151546856 hasConceptScore W2151546856C192562407 @default.
• W2151546856 hasConceptScore W2151546856C204787440 @default.
• W2151546856 hasConceptScore W2151546856C2776164576 @default.
• W2151546856 hasConceptScore W2151546856C2776454340 @default.
• W2151546856 hasConceptScore W2151546856C2777327002 @default.
• W2151546856 hasConceptScore W2151546856C2779980959 @default.
• W2151546856 hasConceptScore W2151546856C2780423099 @default.
• W2151546856 hasConceptScore W2151546856C2908647359 @default.
• W2151546856 hasConceptScore W2151546856C71924100 @default.
• W2151546856 hasConceptScore W2151546856C89429830 @default.
• W2151546856 hasConceptScore W2151546856C99454951 @default.
• W2151546856 hasIssue "6" @default.
• W2151546856 hasLocation W21515468561 @default.
• W2151546856 hasOpenAccess W2151546856 @default.
• W2151546856 hasPrimaryLocation W21515468561 @default.
• W2151546856 hasRelatedWork W100588985 @default.
• W2151546856 hasRelatedWork W2039611308 @default.
• W2151546856 hasRelatedWork W2412887287 @default.
• W2151546856 hasRelatedWork W2416852685 @default.
• W2151546856 hasRelatedWork W2430015200 @default.
• W2151546856 hasRelatedWork W2801475978 @default.
• W2151546856 hasRelatedWork W3121404873 @default.
• W2151546856 hasRelatedWork W4283018424 @default.
• W2151546856 hasRelatedWork W4362467070 @default.
• W2151546856 hasRelatedWork W75493780 @default.
• W2151546856 hasVolume "22" @default.
• W2151546856 isParatext "false" @default.
• W2151546856 isRetracted "false" @default.
• W2151546856 magId "2151546856" @default.
• W2151546856 workType "article" @default.