FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2151561449> ?p ?o ?g. }

• W2151561449 endingPage "95" @default.
• W2151561449 startingPage "87" @default.
• W2151561449 abstract "The Cre recombinase of bacteriophage P1 is a powerful tool for artificial modification of genomic function in mammalian cells. To date, many researchers have studied the enzymatic biochemistry of Cre recombinase in loxP site-specific cleavage and rearrangement, as well as its use in gene technology. However, the intricate mechanisms of Cre-mediated recombination are still poorly understood. For example, more knowledge is needed in order to understand Cre recombinase's dependency on cell cycle, the necessity of other factors for recombination, and the exact nuclear environment that's required at the target locus, in order for recombination to take place in eukaryotic cells. In this study, we showed that P1 Cre-mediated recombination occurred frequently during S-phase of the cell cycle. HeLa cells were synchronized in cell cycle with the thymidine-hydroxyurea block method, and recombinant Cre proteins were fused with HIV-1 TAT protein transduction domains (PTD) in every phase of the cell cycle. Results showed that the transduction of PTD-Cre gave rise to genomic recombination preferentially during the S-phase of cell cycle. These findings will contribute significantly to the development of the Cre/loxP recombination system in vivo." @default.
• W2151561449 created "2016-06-24" @default.
• W2151561449 creator A5013397337 @default.
• W2151561449 creator A5018175091 @default.
• W2151561449 creator A5045234009 @default.
• W2151561449 creator A5069353800 @default.
• W2151561449 creator A5083504416 @default.
• W2151561449 date "2007-10-23" @default.
• W2151561449 modified "2023-09-23" @default.
• W2151561449 title "S Phase-preferential Cre-recombination in Mammalian Cells Revealed by HIV-TAT-PTD-mediated Protein Transduction" @default.
• W2151561449 cites W1616350046 @default.
• W2151561449 cites W1954929088 @default.
• W2151561449 cites W1971028128 @default.
• W2151561449 cites W1973822043 @default.
• W2151561449 cites W1975384668 @default.
• W2151561449 cites W1978146260 @default.
• W2151561449 cites W1978411020 @default.
• W2151561449 cites W1983453394 @default.
• W2151561449 cites W1984795661 @default.
• W2151561449 cites W1987465149 @default.
• W2151561449 cites W1992230504 @default.
• W2151561449 cites W1993439119 @default.
• W2151561449 cites W2014406604 @default.
• W2151561449 cites W2025226992 @default.
• W2151561449 cites W2027718354 @default.
• W2151561449 cites W2028767241 @default.
• W2151561449 cites W2033191256 @default.
• W2151561449 cites W2037733585 @default.
• W2151561449 cites W2039702376 @default.
• W2151561449 cites W2041945142 @default.
• W2151561449 cites W2059390603 @default.
• W2151561449 cites W2059895526 @default.
• W2151561449 cites W2065761939 @default.
• W2151561449 cites W2067963169 @default.
• W2151561449 cites W2072707948 @default.
• W2151561449 cites W2083735421 @default.
• W2151561449 cites W2102025253 @default.
• W2151561449 cites W2107225685 @default.
• W2151561449 cites W2110101886 @default.
• W2151561449 cites W2110487407 @default.
• W2151561449 cites W2121853695 @default.
• W2151561449 cites W2130685717 @default.
• W2151561449 cites W2137627491 @default.
• W2151561449 cites W2146777176 @default.
• W2151561449 cites W2151875814 @default.
• W2151561449 cites W2156704192 @default.
• W2151561449 cites W2158475344 @default.
• W2151561449 cites W2160863389 @default.
• W2151561449 cites W2162262302 @default.
• W2151561449 cites W2166911703 @default.
• W2151561449 doi "https://doi.org/10.1093/jb/mvm198" @default.
• W2151561449 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17965427" @default.
• W2151561449 hasPublicationYear "2007" @default.
• W2151561449 type Work @default.
• W2151561449 sameAs 2151561449 @default.
• W2151561449 citedByCount "6" @default.
• W2151561449 countsByYear W21515614492016 @default.
• W2151561449 countsByYear W21515614492017 @default.
• W2151561449 countsByYear W21515614492020 @default.
• W2151561449 crossrefType "journal-article" @default.
• W2151561449 hasAuthorship W2151561449A5013397337 @default.
• W2151561449 hasAuthorship W2151561449A5018175091 @default.
• W2151561449 hasAuthorship W2151561449A5045234009 @default.
• W2151561449 hasAuthorship W2151561449A5069353800 @default.
• W2151561449 hasAuthorship W2151561449A5083504416 @default.
• W2151561449 hasBestOaLocation W21515614492 @default.
• W2151561449 hasConcept C101434241 @default.
• W2151561449 hasConcept C102230213 @default.
• W2151561449 hasConcept C102414288 @default.
• W2151561449 hasConcept C104317684 @default.
• W2151561449 hasConcept C125929170 @default.
• W2151561449 hasConcept C141035611 @default.
• W2151561449 hasConcept C15152581 @default.
• W2151561449 hasConcept C153911025 @default.
• W2151561449 hasConcept C156695909 @default.
• W2151561449 hasConcept C29537977 @default.
• W2151561449 hasConcept C38027674 @default.
• W2151561449 hasConcept C40767141 @default.
• W2151561449 hasConcept C54355233 @default.
• W2151561449 hasConcept C55493867 @default.
• W2151561449 hasConcept C86803240 @default.
• W2151561449 hasConcept C95444343 @default.
• W2151561449 hasConceptScore W2151561449C101434241 @default.
• W2151561449 hasConceptScore W2151561449C102230213 @default.
• W2151561449 hasConceptScore W2151561449C102414288 @default.
• W2151561449 hasConceptScore W2151561449C104317684 @default.
• W2151561449 hasConceptScore W2151561449C125929170 @default.
• W2151561449 hasConceptScore W2151561449C141035611 @default.
• W2151561449 hasConceptScore W2151561449C15152581 @default.
• W2151561449 hasConceptScore W2151561449C153911025 @default.
• W2151561449 hasConceptScore W2151561449C156695909 @default.
• W2151561449 hasConceptScore W2151561449C29537977 @default.
• W2151561449 hasConceptScore W2151561449C38027674 @default.
• W2151561449 hasConceptScore W2151561449C40767141 @default.
• W2151561449 hasConceptScore W2151561449C54355233 @default.
• W2151561449 hasConceptScore W2151561449C55493867 @default.
• W2151561449 hasConceptScore W2151561449C86803240 @default.
• W2151561449 hasConceptScore W2151561449C95444343 @default.

• next