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• W2151640318 abstract "Recent studies have indicated that trigeminal neurons exhibit central sensitization, an increase in the excitability of neurons within the central nervous system to the extent that a normally innocuous stimulus begins to produce pain after inflammation or injury, and that glial activities play a vital role in this central sensitization. The involvement of glial cells in trigeminal central sensitization contains multiple mechanisms, including interaction with glutamatergic and purinergic receptors. A better understanding of the trigeminal central sensitization mediated by glial cells will help to find potential therapeutic targets and lead to developing new analgesics for orofacial-specific pain with higher efficiency and fewer side-effects." @default.
• W2151640318 created "2016-06-24" @default.
• W2151640318 creator A5054493580 @default.
• W2151640318 date "2008-06-01" @default.
• W2151640318 modified "2023-10-04" @default.
• W2151640318 title "Glial involvement in trigeminal central sensitization" @default.
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• W2151640318 doi "https://doi.org/10.1111/j.1745-7254.2008.00801.x" @default.
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