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- W2151781177 abstract "Probiotics are defined as live microorganisms which when administered in adequate amounts, confer a health benefit to the host. They can positively influence the intestinal microbiota, are safe, and do not show any adverse reactions or side effects even in preterm infants. They have both direct and indirect effects: enhancement of the epithelial barrier, increased adhesion to intestinal mucosa, concomitant inhibition of pathogen adhesion, competitive exclusion of pathogenic microorganisms, production of antimicroorganism substances, and modulation of the immune system.The rationale for the use of probiotics for the treatment of gut microbiota-related disease is the restoration of intestinal homeostasis which is beneficial in several diseases like gastrointestinal disorders, urinary tract diseases, and atopic conditions.In clinical practice, probiotic mixtures have beneficial effects against a wide range of disorders, although the evidence that mixtures are more effective than their component strains is more limited. More randomized and controlled studies are needed in order to describe specific indications of the type of probiotic that must be used in a specific situation, thus better clarifying the structure of the probiotic and its characteristics, selecting the right probiotic for each kind of disease.The initial bacterial colonization of the neonate, called mutualism bacteria host organism, appears to play a crucial role in inducing immunity, and a suboptimal process could have definite consequences. It is necessary to study and find in the near future the possible means to help positively manipulate the gut microbiotia of infants." @default.
- W2151781177 created "2016-06-24" @default.
- W2151781177 creator A5018454327 @default.
- W2151781177 creator A5088282773 @default.
- W2151781177 date "2001-09-01" @default.
- W2151781177 modified "2023-09-23" @default.
- W2151781177 title "BIOTHERAPEUTIC AGENTS IN THE TREATMENT OF INFECTIOUS DIARRHEA" @default.
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- W2151781177 doi "https://doi.org/10.1016/s0889-8553(05)70213-2" @default.
- W2151781177 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11586560" @default.
- W2151781177 hasPublicationYear "2001" @default.
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