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• W2151781207 endingPage "2027" @default.
• W2151781207 startingPage "2020" @default.
• W2151781207 abstract "Objective: This study was performed to determine the favorable effects of garlic on metabolic status and pregnancy outcomes among pregnant women at risk for pre-eclampsia.Methods: This randomized, double-blind, placebo-controlled trial was conducted among 44 pregnant women, primigravida, aged 18–40 years old at 27 weeks' gestation with positive roll-over test. Participants were randomly assigned to receive either one garlic tablet (equal to 400 mg garlic and 1 mg allicin) (n = 22) or placebo (n = 22) once daily for 9 weeks. Fasting blood samples were taken at baseline and after 9 weeks' intervention to measure metabolic profiles and biomarkers of oxidative stress.Results: Administration of garlic compared with the placebo resulted in decreased levels of serum high sensitivity C-reactive protein (hs-CRP) (−1425.90 versus 1360.50 ng/mL, p = 0.01) and increased plasma glutathione (GSH) (+98.10 versus. −49.87 µmol/l, p = 0.03). A trend toward a significant effect of garlic intake on reducing fasting plasma glucose (FPG) (p = 0.07), insulin (p = 0.09) and increasing quantitative insulin sensitivity check (QUICKI) (p = 0.05) was also observed.Conclusion: Consumption of garlic for 9 weeks among pregnant women at risk for pre-eclampsia led to decreased hs-CRP and increased GSH, but did not affect lipid profiles, total antioxidant capacity (TAC) and pregnancy outcomes." @default.
• W2151781207 created "2016-06-24" @default.
• W2151781207 creator A5033686896 @default.
• W2151781207 creator A5047608094 @default.
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• W2151781207 date "2014-11-07" @default.
• W2151781207 modified "2023-10-02" @default.
• W2151781207 title "The favorable effects of garlic intake on metabolic profiles, hs-CRP, biomarkers of oxidative stress and pregnancy outcomes in pregnant women at risk for pre-eclampsia: randomized, double-blind, placebo-controlled trial" @default.
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• W2151781207 doi "https://doi.org/10.3109/14767058.2014.977248" @default.
• W2151781207 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25316559" @default.
• W2151781207 hasPublicationYear "2014" @default.
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