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- W2151847852 startingPage "381" @default.
- W2151847852 abstract "Understanding the role of the diet in determining human health and disease is one major objective of modern nutrition. Mammalian biocomplexity necessitates the incorporation of systems biology technologies into contemporary nutritional research. Metabonomics is a powerful approach that simultaneously measures the low-molecular-weight compounds in a biological sample, enabling the metabolic status of a biological system to be characterized. Such biochemical profiles contain latent information relating to inherent parameters, such as the genotype, and environmental factors, including the diet and gut microbiota. Nutritional metabonomics, or nutrimetabonomics, is being increasingly applied to study molecular interactions between the diet and the global metabolic system. This review discusses three primary areas in which nutrimetabonomics has enjoyed successful application in nutritional research: the illumination of molecular relationships between nutrition and biochemical processes; elucidation of biomarker signatures of food components for use in dietary surveillance; and the study of complex trans-genomic interactions between the mammalian host and its resident gut microbiome. Finally, this review illustrates the potential for nutrimetabonomics in nutritional science as an indispensable tool to achieve personalized nutrition." @default.
- W2151847852 created "2016-06-24" @default.
- W2151847852 creator A5028707065 @default.
- W2151847852 creator A5084502214 @default.
- W2151847852 date "2013-02-28" @default.
- W2151847852 modified "2023-10-17" @default.
- W2151847852 title "Nutrimetabonomics:Applications for Nutritional Sciences, with Specific Reference to Gut Microbial Interactions" @default.
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