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- W2151887732 abstract "Background A double stent system (covered stent in uncovered stent) was designed to provide long-term patency without tumor ingrowth or stent-related complications, such as stent migration, cholecystitis, or pancreatitis. Purpose To investigate the safety and efficacy of double stents in patients with malignant extrahepatic biliary obstructions. Material and Methods This prospective, nonrandomized, multicenter study enrolled 160 consecutive patients (102 men; mean age, 64 years; range, 33–91 years) with malignant extrahepatic biliary obstructions treated with a double stent system from January 2010 to March 2012. Results The technical success rate of the double stent placement was 100%. No stent migration was observed. Procedure-related minor (self-limiting hemobilia [ n = 6] and cholangitis [ n = 2]) and major (pancreatitis [ n = 16], cholecystitis [ n = 3], and hepatic abscess [ n = 2]) complications occurred in a total of 29 patients. The mean serum bilirubin level, which was 8.9 ± 5.6 mg/dL before drainage, decreased to 2.2 ± 4.6 mg/dL 1 month after stent placement ( P < 0.001). Successful internal drainage was achieved in 148 patients (92.5%). During the mean follow-up period of 205 days, acute cholecystitis ( n = 3) and hepatic abscess ( n = 2) occurred in five patients. The median patient survival and stent patency time were 135 days (95% confidence interval [CI], 96–160 days) and 114 days (95% CI, 83–131 days), respectively. Of 153 patients, 22 (14.4%) presented with stent dysfunction due to sludge incrustation ( n = 17), tumor overgrowth ( n = 4), or blood clot ( n = 1), and required repeat intervention. Tumor ingrowth was not observed in any of these patients. Conclusion Percutaneous treatment of malignant extrahepatic biliary obstruction using a double stent safely and effectively achieves internal biliary drainage." @default.
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- W2151887732 date "2015-10-01" @default.
- W2151887732 modified "2023-09-27" @default.
- W2151887732 title "A prospective, multicenter study of a double stent system for palliative treatment of malignant extrahepatic biliary obstructions" @default.
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- W2151887732 doi "https://doi.org/10.1177/0284185114550702" @default.
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