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- W2151933013 abstract "In seven healthy, conscious volunteers, hyper-ventilation from Paco2 35 mm Hg to 23 mm Hg did not change cardiac index (QI), heart rate (HR), stroke volume (SV), total peripheral rete sistance (TPR), or mean right atrial pressure (MRAP). Hyperventilation from Paco2 37 mm Hg to 26 mm Hg during anesthesia with 15–20 per cent cyclopropane decreased QI and SV. When Paco2 was restored to 37 mm Hg by elevating inspired CO: (tidal volume and respiratory rate constant), cardiovascular function was unchanged while the subjects were conscious, and rose only slightly during anesthesia. When the subjects were conscious, hypercapnia induced marked increases in QI, SV, and HR, while TPR and MRAP fell. Cyclopropane, 25–30 per cent, abolished the tachycardia of hypercapnia, and thereby halved the QI response to CO2. However, the QI response to CO- still was better preserved during cyclopropane anesthesia than during halothanc anesthesia or anesthesia with thiopcntal, narcotic and curare." @default.
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- W2151933013 date "1969-11-01" @default.
- W2151933013 modified "2023-09-26" @default.
- W2151933013 title "The Cardiovascular Effects of Carbon Dioxide in Man, Conscious and during Cyclopropane Anesthesia" @default.
- W2151933013 doi "https://doi.org/10.1097/00000542-196911000-00004" @default.
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