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• W2152003723 abstract "In vitro primary cultures of dissociated invertebrate neurons from locust ganglia are used to experimentally investigate the morphological evolution of assemblies of living neurons, as they self-organize from collections of separated cells into elaborated, clustered, networks. At all the different stages of the culture's development, identification of neurons' and neurites' location by means of a dedicated software allows to ultimately extract an adjacency matrix from each image of the culture. In turn, a systematic statistical analysis of a group of topological observables grants us the possibility of quantifying and tracking the progression of the main network's characteristics during the self-organization process of the culture. Our results point to the existence of a particular state corresponding to a small-world network configuration, in which several relevant graph's micro- and meso-scale properties emerge. Finally, we identify the main physical processes ruling the culture's morphological transformations, and embed them into a simplified growth model qualitatively reproducing the overall set of experimental observations." @default.
• W2152003723 created "2016-06-24" @default.
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• W2152003723 date "2014-01-28" @default.
• W2152003723 modified "2023-10-18" @default.
• W2152003723 title "Emergence of Small-World Anatomical Networks in Self-Organizing Clustered Neuronal Cultures" @default.
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• W2152003723 doi "https://doi.org/10.1371/journal.pone.0085828" @default.
• W2152003723 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3904852" @default.
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• W2152003723 hasPublicationYear "2014" @default.
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