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• W2152009255 abstract "Our sense of smell relies on sensitive, selective atomic-scale processes that are initiated when a scent molecule meets specific receptors in the nose. However, the physical mechanisms of detection are not clear. While odorant shape and size are important, experiment indicates these are insufficient. One novel proposal suggests inelastic electron tunneling from a donor to an acceptor mediated by the odorant actuates a receptor, and provides critical discrimination. We test the physical viability of this mechanism using a simple but general model. Using values of key parameters in line with those for other biomolecular systems, we find the proposed mechanism is consistent both with the underlying physics and with observed features of smell, provided the receptor has certain general properties. This mechanism suggests a distinct paradigm for selective molecular interactions at receptors (the swipe card model): recognition and actuation involve size and shape, but also exploit other processes." @default.
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• W2152009255 date "2007-01-16" @default.
• W2152009255 modified "2023-10-14" @default.
• W2152009255 title "Could Humans Recognize Odor by Phonon Assisted Tunneling?" @default.
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• W2152009255 doi "https://doi.org/10.1103/physrevlett.98.038101" @default.
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