Matches in SemOpenAlex for { <https://semopenalex.org/work/W2152037884> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W2152037884 endingPage "176" @default.
- W2152037884 startingPage "171" @default.
- W2152037884 abstract "Brain monoamines are important regulators of affective and cognitive processes and are involved in the aetiology of a number of psychiatric disorders. While methods to probe serotonin and catecholamine function are established, limited methods are available to probe monoamine function as a whole in humans. In the current study, we examined if simultaneous depletion of monoamine precursors can be used as a possible probe of monoamine function. Ten healthy subjects were tested under two treatment conditions; balanced control (B) condition and combined monoamine depletion (CMD) condition. Monoamine precursor depletion was associated with significant reductions in plasma-free tryptophan (46%), tyrosine (74%) and phenylalanine (78%). Greater reductions were achieved for ratios of each precursor to other large neutral amino acids (LNAA); tryptophan/LNAA (86%), tyrosine/LNAA (94%) and phenylalanine/LNAA (94%). Findings suggest that simultaneous depletion of monoamine precursors can achieve significant plasma monoamine depletion in the range expected to affect brain monoamine function." @default.
- W2152037884 created "2016-06-24" @default.
- W2152037884 creator A5014019290 @default.
- W2152037884 creator A5018958936 @default.
- W2152037884 creator A5042275348 @default.
- W2152037884 creator A5065777351 @default.
- W2152037884 date "2004-06-01" @default.
- W2152037884 modified "2023-09-26" @default.
- W2152037884 title "Simultaneous depletion of tryptophan, tyrosine and phenylalanine as an experimental method to probe brain monoamine function in humans" @default.
- W2152037884 cites W1750685322 @default.
- W2152037884 cites W1862470828 @default.
- W2152037884 cites W1969371951 @default.
- W2152037884 cites W2011620025 @default.
- W2152037884 cites W2026737112 @default.
- W2152037884 cites W2034269266 @default.
- W2152037884 cites W2035266273 @default.
- W2152037884 cites W2035824248 @default.
- W2152037884 cites W2054242592 @default.
- W2152037884 cites W2070168159 @default.
- W2152037884 cites W2071359470 @default.
- W2152037884 cites W2078816984 @default.
- W2152037884 cites W2081441090 @default.
- W2152037884 cites W2091627651 @default.
- W2152037884 cites W2092383614 @default.
- W2152037884 cites W2094484291 @default.
- W2152037884 cites W2095629588 @default.
- W2152037884 cites W2099880858 @default.
- W2152037884 cites W2110862208 @default.
- W2152037884 cites W2167927881 @default.
- W2152037884 cites W2183452160 @default.
- W2152037884 doi "https://doi.org/10.1017/s1461145703004073" @default.
- W2152037884 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/14962353" @default.
- W2152037884 hasPublicationYear "2004" @default.
- W2152037884 type Work @default.
- W2152037884 sameAs 2152037884 @default.
- W2152037884 citedByCount "17" @default.
- W2152037884 countsByYear W21520378842012 @default.
- W2152037884 countsByYear W21520378842018 @default.
- W2152037884 countsByYear W21520378842019 @default.
- W2152037884 countsByYear W21520378842020 @default.
- W2152037884 countsByYear W21520378842022 @default.
- W2152037884 crossrefType "journal-article" @default.
- W2152037884 hasAuthorship W2152037884A5014019290 @default.
- W2152037884 hasAuthorship W2152037884A5018958936 @default.
- W2152037884 hasAuthorship W2152037884A5042275348 @default.
- W2152037884 hasAuthorship W2152037884A5065777351 @default.
- W2152037884 hasBestOaLocation W21520378841 @default.
- W2152037884 hasConcept C126322002 @default.
- W2152037884 hasConcept C134018914 @default.
- W2152037884 hasConcept C170493617 @default.
- W2152037884 hasConcept C185592680 @default.
- W2152037884 hasConcept C187714386 @default.
- W2152037884 hasConcept C2775864247 @default.
- W2152037884 hasConcept C2775894120 @default.
- W2152037884 hasConcept C2776165026 @default.
- W2152037884 hasConcept C2776706248 @default.
- W2152037884 hasConcept C2777431362 @default.
- W2152037884 hasConcept C513476851 @default.
- W2152037884 hasConcept C515207424 @default.
- W2152037884 hasConcept C55493867 @default.
- W2152037884 hasConcept C71924100 @default.
- W2152037884 hasConceptScore W2152037884C126322002 @default.
- W2152037884 hasConceptScore W2152037884C134018914 @default.
- W2152037884 hasConceptScore W2152037884C170493617 @default.
- W2152037884 hasConceptScore W2152037884C185592680 @default.
- W2152037884 hasConceptScore W2152037884C187714386 @default.
- W2152037884 hasConceptScore W2152037884C2775864247 @default.
- W2152037884 hasConceptScore W2152037884C2775894120 @default.
- W2152037884 hasConceptScore W2152037884C2776165026 @default.
- W2152037884 hasConceptScore W2152037884C2776706248 @default.
- W2152037884 hasConceptScore W2152037884C2777431362 @default.
- W2152037884 hasConceptScore W2152037884C513476851 @default.
- W2152037884 hasConceptScore W2152037884C515207424 @default.
- W2152037884 hasConceptScore W2152037884C55493867 @default.
- W2152037884 hasConceptScore W2152037884C71924100 @default.
- W2152037884 hasIssue "2" @default.
- W2152037884 hasLocation W21520378841 @default.
- W2152037884 hasLocation W21520378842 @default.
- W2152037884 hasOpenAccess W2152037884 @default.
- W2152037884 hasPrimaryLocation W21520378841 @default.
- W2152037884 hasRelatedWork W1665528006 @default.
- W2152037884 hasRelatedWork W2029534735 @default.
- W2152037884 hasRelatedWork W2046425777 @default.
- W2152037884 hasRelatedWork W2060248845 @default.
- W2152037884 hasRelatedWork W2091962258 @default.
- W2152037884 hasRelatedWork W2109896425 @default.
- W2152037884 hasRelatedWork W2110080591 @default.
- W2152037884 hasRelatedWork W2112684472 @default.
- W2152037884 hasRelatedWork W2115482187 @default.
- W2152037884 hasRelatedWork W2152037884 @default.
- W2152037884 hasVolume "7" @default.
- W2152037884 isParatext "false" @default.
- W2152037884 isRetracted "false" @default.
- W2152037884 magId "2152037884" @default.
- W2152037884 workType "article" @default.