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- W2152043695 abstract "The aim of the present experiment was to test whether vasopressin modulates pain perception in man. Twenty-four male volunteers participated in four sessions, each 2 weeks apart. After an adaptation session the subjects were treated intranasally with either 30 or 60 μg desmopressin (DDAVP) or placebo according to a cross-over double-blind design. Pain induction involved mechanical, thermal, and ischemic stimulation. DDAVP had no unitary effects on pain perception in the different pain tests. The 30 μg dose induced sensitization to thermal stimuli. Neither treatment influenced ischemic pain perception. The mechanical pain threshold of the index finger was increased by the 60 μg dose only. After treatment with either dosage of DDAVP the subjccts generally tolerated the pressure on their index finger for a longer time than after placebo treatment." @default.
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- W2152043695 date "1996-01-01" @default.
- W2152043695 modified "2023-09-23" @default.
- W2152043695 title "Modulation of pain perception in man by a vasopressin analogue" @default.
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- W2152043695 doi "https://doi.org/10.1016/0196-9781(96)00034-4" @default.
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