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• W2152091242 abstract "Cancer initiation and progression can involve microRNAs (miRNA), which are small noncoding RNAs that can regulate gene expression. Their expression profiles can be used for the classification, diagnosis, and prognosis of human malignancies. Loss or amplification of miRNA genes has been reported in a variety of cancers, and altered patterns of miRNA expression may affect cell cycle and survival programs. Germ-line and somatic mutations in miRNAs or polymorphisms in the mRNAs targeted by miRNAs may also contribute to cancer predisposition and progression. We propose that alterations in miRNA genes play a critical role in the pathophysiology of many, perhaps all, human cancers." @default.
• W2152091242 created "2016-06-24" @default.
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• W2152091242 date "2006-08-01" @default.
• W2152091242 modified "2023-10-10" @default.
• W2152091242 title "MicroRNA-Cancer Connection: The Beginning of a New Tale" @default.
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• W2152091242 doi "https://doi.org/10.1158/0008-5472.can-06-0800" @default.
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