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• W2152134477 abstract "Streptococcus parasanguis is a primary colonizer of dental plaque and a major player in subacute bacterial endocarditis. In the present study, the authors report that an ORF (ORF3) located 77 bp downstream of the fimA operon on the S. parasanguis FW213 chromosome complements an Escherichia coli thiol peroxidase (tpx) mutation in glutamine synthetase (GS) protection assays and that GS is protected by the ORF3 gene product in S. parasanguis cell extracts. In addition, the putative streptococcal peroxidase (Tpx(Sp)) protects S. parasanguis from stress caused by H2O2 and is induced by oxygen, as revealed by Northern blot analysis. Taken collectively, these findings support a thiol-dependent antioxidant activity for Tpx in S. parasanguis." @default.
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• W2152134477 date "2002-03-01" @default.
• W2152134477 modified "2023-10-01" @default.
• W2152134477 title "Evidence that ORF3 at the Streptococcus parasanguis fimA locus encodes a thiol-specific antioxidant" @default.
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• W2152134477 doi "https://doi.org/10.1099/00221287-148-3-755" @default.
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