Matches in SemOpenAlex for { <https://semopenalex.org/work/W2152173525> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W2152173525 endingPage "205" @default.
- W2152173525 startingPage "199" @default.
- W2152173525 abstract "To study the correlation between the yield of virus-induced interferon (IFN) production in leukocyte cultures and the risk of recurrent respiratory infections.A sample of 71 consecutive children enrolled in the Finnish Otitis Media Cohort Study were selected. Children suffering from frequently recurring respiratory infections (FRRIs) were defined as the highest quintile of the entire cohort of 329 children, as regards the number of upper respiratory infections (URIs) and/or episodes of acute otitis media (AOM) during the follow-up period from 2 to 24 months.In the sample of 71 children, there were 18 children with FRRI (> or = 9 URI and/or > or = 4 AOM). Leukocyte cultures, prepared from blood drawn from these 18 children at 6 months of age, produced lower yields of IFN than those of the remaining 53 children, when stimulated with adenovirus (P <0.001), coronavirus (P<0.001) or rhinovirus (P=0.002). The difference in IFN yields was even greater (P<0.001 with all three viruses) if the comparison was made between children with FRRI and those with no or maximally one URI during the follow-up period. When the IFN production capacity induced by rhinovirus was measured at the age of 24 months, a statistically significant difference between the children with FRRI and the others was also seen (P=0.002). Influenza A virus-induced IFN production capacity did not differ between the groups at either age (P=0.209).Lowered IFN responses in children suffering from recurrent URIs and/or AOM may, in a subgroup of the children, be due to a genetic property of the child. However, because of the great interindividual variations, we cannot use the IFN production capacity as such for prediction of forthcoming respiratory infections and/or otitis media." @default.
- W2152173525 created "2016-06-24" @default.
- W2152173525 creator A5008011329 @default.
- W2152173525 creator A5008453318 @default.
- W2152173525 creator A5030319937 @default.
- W2152173525 creator A5071808871 @default.
- W2152173525 creator A5074159991 @default.
- W2152173525 creator A5081028981 @default.
- W2152173525 date "1999-12-01" @default.
- W2152173525 modified "2023-09-26" @default.
- W2152173525 title "Lowered yields of virus-induced interferon production in leukocyte cultures and risk of recurrent respiratory infections in children" @default.
- W2152173525 cites W129762789 @default.
- W2152173525 cites W1891437937 @default.
- W2152173525 cites W1972122754 @default.
- W2152173525 cites W1983831698 @default.
- W2152173525 cites W1993947411 @default.
- W2152173525 cites W1999080840 @default.
- W2152173525 cites W2004829503 @default.
- W2152173525 cites W2010399256 @default.
- W2152173525 cites W2026352048 @default.
- W2152173525 cites W2044720356 @default.
- W2152173525 cites W2064969643 @default.
- W2152173525 cites W2118159647 @default.
- W2152173525 cites W2148126661 @default.
- W2152173525 cites W2156121631 @default.
- W2152173525 cites W2163631501 @default.
- W2152173525 cites W2318003275 @default.
- W2152173525 cites W2409133651 @default.
- W2152173525 doi "https://doi.org/10.1016/s1386-6532(99)00056-6" @default.
- W2152173525 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7129541" @default.
- W2152173525 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10614857" @default.
- W2152173525 hasPublicationYear "1999" @default.
- W2152173525 type Work @default.
- W2152173525 sameAs 2152173525 @default.
- W2152173525 citedByCount "27" @default.
- W2152173525 countsByYear W21521735252014 @default.
- W2152173525 countsByYear W21521735252016 @default.
- W2152173525 countsByYear W21521735252017 @default.
- W2152173525 countsByYear W21521735252020 @default.
- W2152173525 crossrefType "journal-article" @default.
- W2152173525 hasAuthorship W2152173525A5008011329 @default.
- W2152173525 hasAuthorship W2152173525A5008453318 @default.
- W2152173525 hasAuthorship W2152173525A5030319937 @default.
- W2152173525 hasAuthorship W2152173525A5071808871 @default.
- W2152173525 hasAuthorship W2152173525A5074159991 @default.
- W2152173525 hasAuthorship W2152173525A5081028981 @default.
- W2152173525 hasBestOaLocation W21521735251 @default.
- W2152173525 hasConcept C126322002 @default.
- W2152173525 hasConcept C141071460 @default.
- W2152173525 hasConcept C187212893 @default.
- W2152173525 hasConcept C203014093 @default.
- W2152173525 hasConcept C2522874641 @default.
- W2152173525 hasConcept C2776178377 @default.
- W2152173525 hasConcept C2776439223 @default.
- W2152173525 hasConcept C2779278377 @default.
- W2152173525 hasConcept C2908979688 @default.
- W2152173525 hasConcept C534529494 @default.
- W2152173525 hasConcept C71924100 @default.
- W2152173525 hasConcept C72563966 @default.
- W2152173525 hasConceptScore W2152173525C126322002 @default.
- W2152173525 hasConceptScore W2152173525C141071460 @default.
- W2152173525 hasConceptScore W2152173525C187212893 @default.
- W2152173525 hasConceptScore W2152173525C203014093 @default.
- W2152173525 hasConceptScore W2152173525C2522874641 @default.
- W2152173525 hasConceptScore W2152173525C2776178377 @default.
- W2152173525 hasConceptScore W2152173525C2776439223 @default.
- W2152173525 hasConceptScore W2152173525C2779278377 @default.
- W2152173525 hasConceptScore W2152173525C2908979688 @default.
- W2152173525 hasConceptScore W2152173525C534529494 @default.
- W2152173525 hasConceptScore W2152173525C71924100 @default.
- W2152173525 hasConceptScore W2152173525C72563966 @default.
- W2152173525 hasIssue "3" @default.
- W2152173525 hasLocation W21521735251 @default.
- W2152173525 hasLocation W21521735252 @default.
- W2152173525 hasLocation W21521735253 @default.
- W2152173525 hasLocation W21521735254 @default.
- W2152173525 hasOpenAccess W2152173525 @default.
- W2152173525 hasPrimaryLocation W21521735251 @default.
- W2152173525 hasRelatedWork W1995643950 @default.
- W2152173525 hasRelatedWork W2098479392 @default.
- W2152173525 hasRelatedWork W2143201035 @default.
- W2152173525 hasRelatedWork W2329673641 @default.
- W2152173525 hasRelatedWork W2342468907 @default.
- W2152173525 hasRelatedWork W2382463158 @default.
- W2152173525 hasRelatedWork W2410418192 @default.
- W2152173525 hasRelatedWork W2950165324 @default.
- W2152173525 hasRelatedWork W3027746149 @default.
- W2152173525 hasRelatedWork W4236397368 @default.
- W2152173525 hasVolume "14" @default.
- W2152173525 isParatext "false" @default.
- W2152173525 isRetracted "false" @default.
- W2152173525 magId "2152173525" @default.
- W2152173525 workType "article" @default.