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- W2152182181 abstract "See article by Shi et al. [5] (pages 217–225) in this issue. Atrial fibrillation (AF) is associated with numerous pathologies, as well as the normal aging process. The most common pathologies are valvular and ischemic heart disease, hyperthyroidism, hypertension, and cardiomyopathies. Less common etiologies, but still clearly associated with AF, include cardiac tumors, various inflammatory diseases, abnormal autonomic tone, and substance abuse [1]. What has become clear over the last 100 years of AF research is that at the electrophysiological level there are four interacting substrates that contribute to AF. These include: (1) premature impulse formation; (2) the magnitude and distribution of repolarization and refractory period; (3) the magnitude, distribution, and anisotropy of propagation velocity; and (4) the microscopic and macroscopic anatomy of the atria. The interaction of these factors determines … * Tel.: +1-314-362-8300; fax: +1-314-361-8706" @default.
- W2152182181 created "2016-06-24" @default.
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- W2152182181 date "2001-11-01" @default.
- W2152182181 modified "2023-09-25" @default.
- W2152182181 title "Establishing the link between a specific pathology and atrial fibrillation" @default.
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- W2152182181 doi "https://doi.org/10.1016/s0008-6363(01)00455-2" @default.
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