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• W2152215476 endingPage "1190" @default.
• W2152215476 startingPage "1171" @default.
• W2152215476 abstract "SUMMARY Enveloped viruses mature by budding at cellular membranes. It has been generally thought that this process is driven by interactions between the viral transmembrane proteins and the internal virion components (core, capsid, or nucleocapsid). This model was particularly applicable to alphaviruses, which require both spike proteins and a nucleocapsid for budding. However, genetic studies have clearly shown that the retrovirus core protein, i.e., the Gag protein, is able to form enveloped particles by itself. Also, budding of negative-strand RNA viruses (rhabdoviruses, orthomyxoviruses, and paramyxoviruses) seems to be accomplished mainly by internal components, most probably the matrix protein, since the spike proteins are not absolutely required for budding of these viruses either. In contrast, budding of coronavirus particles can occur in the absence of the nucleocapsid and appears to require two membrane proteins only. Biochemical and structural data suggest that the proteins, which play a key role in budding, drive this process by forming a three-dimensional (cage-like) protein lattice at the surface of or within the membrane. Similarly, recent electron microscopic studies revealed that the alphavirus spike proteins are also engaged in extensive lateral interactions, forming a dense protein shell at the outer surface of the viral envelope. On the basis of these data, we propose that the budding of enveloped viruses in general is governed by lateral interactions between peripheral or integral membrane proteins. This new concept also provides answers to the question of how viral and cellular membrane proteins are sorted during budding. In addition, it has implications for the mechanism by which the virion is uncoated during virus entry." @default.
• W2152215476 created "2016-06-24" @default.
• W2152215476 creator A5022065785 @default.
• W2152215476 creator A5058186910 @default.
• W2152215476 creator A5062691955 @default.
• W2152215476 date "1998-12-01" @default.
• W2152215476 modified "2023-10-15" @default.
• W2152215476 title "Virus Maturation by Budding" @default.
• W2152215476 cites W145694393 @default.
• W2152215476 cites W1480135811 @default.
• W2152215476 cites W1490002353 @default.
• W2152215476 cites W1492423760 @default.
• W2152215476 cites W1493918622 @default.
• W2152215476 cites W1499668219 @default.
• W2152215476 cites W1508323061 @default.
• W2152215476 cites W1509948560 @default.
• W2152215476 cites W1516548724 @default.
• W2152215476 cites W1516991153 @default.
• W2152215476 cites W151727479 @default.
• W2152215476 cites W1519226646 @default.
• W2152215476 cites W1520951540 @default.
• W2152215476 cites W1523743194 @default.
• W2152215476 cites W1525285670 @default.
• W2152215476 cites W1527584380 @default.
• W2152215476 cites W1529440054 @default.
• W2152215476 cites W1530200703 @default.
• W2152215476 cites W1531241043 @default.
• W2152215476 cites W1531671267 @default.
• W2152215476 cites W1533777823 @default.
• W2152215476 cites W1536442034 @default.
• W2152215476 cites W1542639585 @default.
• W2152215476 cites W1546594087 @default.
• W2152215476 cites W1547203457 @default.
• W2152215476 cites W1555908033 @default.
• W2152215476 cites W1557805105 @default.
• W2152215476 cites W1557860493 @default.
• W2152215476 cites W1562279356 @default.
• W2152215476 cites W1566615124 @default.
• W2152215476 cites W1566859727 @default.
• W2152215476 cites W1567879434 @default.
• W2152215476 cites W1572160129 @default.
• W2152215476 cites W1579191879 @default.
• W2152215476 cites W1580152765 @default.
• W2152215476 cites W1582853114 @default.
• W2152215476 cites W1583571071 @default.
• W2152215476 cites W1584375422 @default.
• W2152215476 cites W1585341952 @default.
• W2152215476 cites W1589157702 @default.
• W2152215476 cites W1589223688 @default.
• W2152215476 cites W1589737225 @default.
• W2152215476 cites W1590534776 @default.
• W2152215476 cites W1592259743 @default.
• W2152215476 cites W1599129674 @default.
• W2152215476 cites W1600904956 @default.
• W2152215476 cites W1602267385 @default.
• W2152215476 cites W1608128491 @default.
• W2152215476 cites W1609994548 @default.
• W2152215476 cites W1624020394 @default.
• W2152215476 cites W1631641322 @default.
• W2152215476 cites W1632486555 @default.
• W2152215476 cites W1632798454 @default.
• W2152215476 cites W1640609127 @default.
• W2152215476 cites W1657414671 @default.
• W2152215476 cites W1659840293 @default.
• W2152215476 cites W1692102943 @default.
• W2152215476 cites W1700316245 @default.
• W2152215476 cites W170446279 @default.
• W2152215476 cites W1748541083 @default.
• W2152215476 cites W1758624082 @default.
• W2152215476 cites W1760183277 @default.
• W2152215476 cites W1762245052 @default.
• W2152215476 cites W1776574444 @default.
• W2152215476 cites W1785639469 @default.
• W2152215476 cites W1806998329 @default.
• W2152215476 cites W1807429639 @default.
• W2152215476 cites W1823954631 @default.
• W2152215476 cites W1825333988 @default.
• W2152215476 cites W1829655256 @default.
• W2152215476 cites W1855484651 @default.
• W2152215476 cites W1863094910 @default.
• W2152215476 cites W1863653662 @default.
• W2152215476 cites W1871011833 @default.
• W2152215476 cites W1875262379 @default.
• W2152215476 cites W1877677658 @default.
• W2152215476 cites W1894623846 @default.
• W2152215476 cites W1896763970 @default.
• W2152215476 cites W1899357709 @default.
• W2152215476 cites W1903380786 @default.
• W2152215476 cites W1905230553 @default.
• W2152215476 cites W1930745477 @default.
• W2152215476 cites W1933233179 @default.
• W2152215476 cites W1935409219 @default.
• W2152215476 cites W1937118383 @default.
• W2152215476 cites W1950902800 @default.
• W2152215476 cites W1952779451 @default.
• W2152215476 cites W1956545241 @default.
• W2152215476 cites W1965095658 @default.
• W2152215476 cites W1965805827 @default.

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