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• W2152243318 startingPage "166" @default.
• W2152243318 abstract "Microautophagy involves direct invagination and fission of the vacuolar/lysosomal membrane under nutrient limitation. This occurs by an autophagic tube, a specialized vacuolar membrane invagination that pinches off vesicles into the vacuolar lumen. In this study we have identified the VTC (vacuolar transporter chaperone) complex as required for microautophagy. The VTC complex is present on the ER and vacuoles and at the cell periphery. On induction of autophagy by nutrient limitation the VTC complex is recruited to and concentrated on vacuoles. The VTC complex is inhomogeneously distributed within the vacuolar membranes, showing an enrichment on autophagic tubes. Deletion of the VTC complex blocks microautophagic uptake into vacuoles. The mutants still form autophagic tubes but the production of microautophagic vesicles from their tips is impaired. In line with this, affinity-purified antibodies to the Vtc proteins inhibit microautophagic uptake in a reconstituted system in vitro. Our data suggest that the VTC complex is an important constituent of autophagic tubes and that it is required for scission of microautophagic vesicles from these tubes." @default.
• W2152243318 created "2016-06-24" @default.
• W2152243318 creator A5049541548 @default.
• W2152243318 creator A5069380668 @default.
• W2152243318 creator A5076485627 @default.
• W2152243318 creator A5088617574 @default.
• W2152243318 date "2007-01-01" @default.
• W2152243318 modified "2023-10-05" @default.
• W2152243318 title "The Vacuolar Transporter Chaperone (VTC) Complex Is Required for Microautophagy" @default.
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• W2152243318 cites W1498832295 @default.
• W2152243318 cites W1563672361 @default.
• W2152243318 cites W1605872139 @default.
• W2152243318 cites W1618106381 @default.
• W2152243318 cites W1621428842 @default.
• W2152243318 cites W1894512944 @default.
• W2152243318 cites W1936097558 @default.
• W2152243318 cites W1965476757 @default.
• W2152243318 cites W1967897161 @default.
• W2152243318 cites W1968098564 @default.
• W2152243318 cites W1968456917 @default.
• W2152243318 cites W1969449813 @default.
• W2152243318 cites W1972523086 @default.
• W2152243318 cites W1973130575 @default.
• W2152243318 cites W1978751572 @default.
• W2152243318 cites W1987159249 @default.
• W2152243318 cites W1992274725 @default.
• W2152243318 cites W2003114036 @default.
• W2152243318 cites W2010228532 @default.
• W2152243318 cites W2010247270 @default.
• W2152243318 cites W2011580247 @default.
• W2152243318 cites W2012451546 @default.
• W2152243318 cites W2019897261 @default.
• W2152243318 cites W2020978927 @default.
• W2152243318 cites W2021094611 @default.
• W2152243318 cites W2022704511 @default.
• W2152243318 cites W2022828571 @default.
• W2152243318 cites W2024142216 @default.
• W2152243318 cites W2027716300 @default.
• W2152243318 cites W2029098242 @default.
• W2152243318 cites W2029638626 @default.
• W2152243318 cites W2029870632 @default.
• W2152243318 cites W2031811477 @default.
• W2152243318 cites W2034162523 @default.
• W2152243318 cites W2036058199 @default.
• W2152243318 cites W2037710668 @default.
• W2152243318 cites W2043690695 @default.
• W2152243318 cites W2045201133 @default.
• W2152243318 cites W2047095039 @default.
• W2152243318 cites W2049842278 @default.
• W2152243318 cites W2066727453 @default.
• W2152243318 cites W2066800765 @default.
• W2152243318 cites W2067238658 @default.
• W2152243318 cites W2067692987 @default.
• W2152243318 cites W2069603893 @default.
• W2152243318 cites W2072310161 @default.
• W2152243318 cites W2083895131 @default.
• W2152243318 cites W2093521208 @default.
• W2152243318 cites W2094866226 @default.
• W2152243318 cites W2096054930 @default.
• W2152243318 cites W2096794529 @default.
• W2152243318 cites W2097630079 @default.
• W2152243318 cites W2106569931 @default.
• W2152243318 cites W2111362374 @default.
• W2152243318 cites W2115886998 @default.
• W2152243318 cites W2120507868 @default.
• W2152243318 cites W2121523680 @default.
• W2152243318 cites W2123661270 @default.
• W2152243318 cites W2126551164 @default.
• W2152243318 cites W2126801593 @default.
• W2152243318 cites W2129712803 @default.
• W2152243318 cites W2133830708 @default.
• W2152243318 cites W2137719759 @default.
• W2152243318 cites W2141075240 @default.
• W2152243318 cites W2145272227 @default.
• W2152243318 cites W2150038290 @default.
• W2152243318 cites W2154046032 @default.
• W2152243318 cites W2154383549 @default.
• W2152243318 cites W2156320420 @default.
• W2152243318 cites W2156848898 @default.
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• W2152243318 cites W2157778451 @default.
• W2152243318 cites W2164319104 @default.
• W2152243318 cites W2168427881 @default.
• W2152243318 cites W2170333695 @default.
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• W2152243318 doi "https://doi.org/10.1091/mbc.e06-08-0664" @default.
• W2152243318 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1751332" @default.
• W2152243318 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17079729" @default.
• W2152243318 hasPublicationYear "2007" @default.
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