Matches in SemOpenAlex for { <https://semopenalex.org/work/W2152257935> ?p ?o ?g. }
Showing items 1 to 84 of
84
with 100 items per page.
- W2152257935 endingPage "6" @default.
- W2152257935 startingPage "73" @default.
- W2152257935 abstract "Cigarette smoke (CS) is the main inducer of oral cancer, increasing its prevalence by 4-7 times.We examined the suitability of cell models SCC-25 and SCC-15 for studying effects of CS on oral cancer cells and whether CS significantly affects the cell cycle using fluorescence-activated cell sorting assays.There was significant change in the fraction of SCC-15 cells in pre-G1 state following CS exposure. At 60 and 90 min, increase in the pre-G1 cell fraction was 118% (p<0.05) and 135% (p<0.01) respectively. The G2/M cell fraction was significantly lower following CS exposure. At 90 and 120 min following CS exposure, the G2/M fraction levels had declined by 44% (p<0.05) and 34% (p<0.01) respectively. Results for SCC-25 cells were similar. At 90 and 120 min following CS exposure, the pre-G1 fraction of the cells increased by 230% and 550%, respectively (p<0.01). At 120 min of CS exposure, the fraction of G2/M cells was lower by 47% (p<0.05) compared to controls.CS profoundly affects the cell-cycle distribution in both SCC-15 and SCC-25 oral cancer cellular models. Such effects have been associated with DNA damage and carcinogenesis. Both models are useful for studying oral cancer pathogenesis." @default.
- W2152257935 created "2016-06-24" @default.
- W2152257935 creator A5046097964 @default.
- W2152257935 creator A5050201213 @default.
- W2152257935 date "2015-03-15" @default.
- W2152257935 modified "2023-09-23" @default.
- W2152257935 title "Cigarette smoke-induced effects on the cell cycle in oral cancer cells: reduction of G2/M fraction." @default.
- W2152257935 cites W1501512050 @default.
- W2152257935 cites W1555487519 @default.
- W2152257935 cites W1969775662 @default.
- W2152257935 cites W1982997869 @default.
- W2152257935 cites W1987029158 @default.
- W2152257935 cites W2008416165 @default.
- W2152257935 cites W2009639237 @default.
- W2152257935 cites W2020418567 @default.
- W2152257935 cites W2083192586 @default.
- W2152257935 cites W2093749372 @default.
- W2152257935 cites W2147783172 @default.
- W2152257935 cites W2151633680 @default.
- W2152257935 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25770190" @default.
- W2152257935 hasPublicationYear "2015" @default.
- W2152257935 type Work @default.
- W2152257935 sameAs 2152257935 @default.
- W2152257935 citedByCount "3" @default.
- W2152257935 countsByYear W21522579352018 @default.
- W2152257935 countsByYear W21522579352022 @default.
- W2152257935 crossrefType "journal-article" @default.
- W2152257935 hasAuthorship W2152257935A5046097964 @default.
- W2152257935 hasAuthorship W2152257935A5050201213 @default.
- W2152257935 hasConcept C114246631 @default.
- W2152257935 hasConcept C121608353 @default.
- W2152257935 hasConcept C126322002 @default.
- W2152257935 hasConcept C134018914 @default.
- W2152257935 hasConcept C1491633281 @default.
- W2152257935 hasConcept C149629883 @default.
- W2152257935 hasConcept C153911025 @default.
- W2152257935 hasConcept C16685009 @default.
- W2152257935 hasConcept C178790620 @default.
- W2152257935 hasConcept C185592680 @default.
- W2152257935 hasConcept C190283241 @default.
- W2152257935 hasConcept C29537977 @default.
- W2152257935 hasConcept C55493867 @default.
- W2152257935 hasConcept C555283112 @default.
- W2152257935 hasConcept C71924100 @default.
- W2152257935 hasConcept C86803240 @default.
- W2152257935 hasConcept C96232424 @default.
- W2152257935 hasConceptScore W2152257935C114246631 @default.
- W2152257935 hasConceptScore W2152257935C121608353 @default.
- W2152257935 hasConceptScore W2152257935C126322002 @default.
- W2152257935 hasConceptScore W2152257935C134018914 @default.
- W2152257935 hasConceptScore W2152257935C1491633281 @default.
- W2152257935 hasConceptScore W2152257935C149629883 @default.
- W2152257935 hasConceptScore W2152257935C153911025 @default.
- W2152257935 hasConceptScore W2152257935C16685009 @default.
- W2152257935 hasConceptScore W2152257935C178790620 @default.
- W2152257935 hasConceptScore W2152257935C185592680 @default.
- W2152257935 hasConceptScore W2152257935C190283241 @default.
- W2152257935 hasConceptScore W2152257935C29537977 @default.
- W2152257935 hasConceptScore W2152257935C55493867 @default.
- W2152257935 hasConceptScore W2152257935C555283112 @default.
- W2152257935 hasConceptScore W2152257935C71924100 @default.
- W2152257935 hasConceptScore W2152257935C86803240 @default.
- W2152257935 hasConceptScore W2152257935C96232424 @default.
- W2152257935 hasIssue "2" @default.
- W2152257935 hasLocation W21522579351 @default.
- W2152257935 hasOpenAccess W2152257935 @default.
- W2152257935 hasPrimaryLocation W21522579351 @default.
- W2152257935 hasRelatedWork W1518035471 @default.
- W2152257935 hasRelatedWork W2341629494 @default.
- W2152257935 hasRelatedWork W2350294409 @default.
- W2152257935 hasRelatedWork W2363671651 @default.
- W2152257935 hasRelatedWork W2379793373 @default.
- W2152257935 hasRelatedWork W2501960686 @default.
- W2152257935 hasRelatedWork W2892874010 @default.
- W2152257935 hasRelatedWork W2906524453 @default.
- W2152257935 hasRelatedWork W3012168770 @default.
- W2152257935 hasRelatedWork W3174627784 @default.
- W2152257935 hasVolume "12" @default.
- W2152257935 isParatext "false" @default.
- W2152257935 isRetracted "false" @default.
- W2152257935 magId "2152257935" @default.
- W2152257935 workType "article" @default.