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- W2152288900 abstract "Abstract. Clinical neuropathy has been studied before and after renal transplantation in 27 patients who received a transplant from a close relative. With one exception, excluded from the follow‐up study, azotemia was eliminated in all patients within the first week. Three patients later died from rejection and two from extrarenal complications. The observation period ranged from 1 to 31 months (average 12). The material was divided into two groups: I. Among 14 patients with normal vibratory perception threshold (VPT) on the big toe before transplantation, four had clinical signs of mild neuropathy which disappeared 1–3 months after transplantation. II. Thirteen patients with elevated VPT had other clinical signs of a moderate to severe neuropathy. The remission after transplantation was two‐phasic with an early rapid and a late slow phase. A marked reduction in the VPT during the first weeks preceded the disappearance of sensory and motor signs, which took place in a distalward direction. Muscular weakness and wasting and reflex disturbances were among the latest signs to disappear. A prognostic evaluation of the neuropathy was possible after about 6 months. Clinical signs which had shown no tendency to regress at that time apparently became permanent sequelae. After 2 1/2 years two patients still had paralysis of distal muscles in the legs and of isolated muscles in the hands. The ankle reflexes and the vibration sense on the big toe were extinct and there was severe hypesthesia of the feet." @default.
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- W2152288900 date "1974-01-12" @default.
- W2152288900 modified "2023-10-16" @default.
- W2152288900 title "THE PERIPHERAL NERVE FUNCTION IN CHRONIC RENAL FAILURE" @default.
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- W2152288900 doi "https://doi.org/10.1111/j.0954-6820.1974.tb08118.x" @default.
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