FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2152363872> ?p ?o ?g. }

• W2152363872 endingPage "e1000160" @default.
• W2152363872 startingPage "e1000160" @default.
• W2152363872 abstract "The evolutionary timing and spread of the Mycobacterium tuberculosis complex (MTBC), one of the most successful groups of bacterial pathogens, remains largely unknown. Here, using mycobacterial tandem repeat sequences as genetic markers, we show that the MTBC consists of two independent clades, one composed exclusively of M. tuberculosis lineages from humans and the other composed of both animal and human isolates. The latter also likely derived from a human pathogenic lineage, supporting the hypothesis of an original human host. Using Bayesian statistics and experimental data on the variability of the mycobacterial markers in infected patients, we estimated the age of the MTBC at 40,000 years, coinciding with the expansion of “modern” human populations out of Africa. Furthermore, coalescence analysis revealed a strong and recent demographic expansion in almost all M. tuberculosis lineages, which coincides with the human population explosion over the last two centuries. These findings thus unveil the dynamic dimension of the association between human host and pathogen populations." @default.
• W2152363872 created "2016-06-24" @default.
• W2152363872 creator A5009745059 @default.
• W2152363872 creator A5009991935 @default.
• W2152363872 creator A5019583674 @default.
• W2152363872 creator A5025754154 @default.
• W2152363872 creator A5041529580 @default.
• W2152363872 creator A5043529126 @default.
• W2152363872 creator A5043828779 @default.
• W2152363872 creator A5050702223 @default.
• W2152363872 creator A5057991295 @default.
• W2152363872 creator A5063110744 @default.
• W2152363872 creator A5063438724 @default.
• W2152363872 creator A5089013920 @default.
• W2152363872 creator A5089859440 @default.
• W2152363872 date "2008-09-26" @default.
• W2152363872 modified "2023-10-18" @default.
• W2152363872 title "Origin, Spread and Demography of the Mycobacterium tuberculosis Complex" @default.
• W2152363872 cites W1886027281 @default.
• W2152363872 cites W1922405592 @default.
• W2152363872 cites W1932965419 @default.
• W2152363872 cites W1945353891 @default.
• W2152363872 cites W1969464199 @default.
• W2152363872 cites W1977109690 @default.
• W2152363872 cites W1985986410 @default.
• W2152363872 cites W1999809115 @default.
• W2152363872 cites W2005100412 @default.
• W2152363872 cites W2015427377 @default.
• W2152363872 cites W2018228576 @default.
• W2152363872 cites W2039704296 @default.
• W2152363872 cites W2044648876 @default.
• W2152363872 cites W2052550780 @default.
• W2152363872 cites W2052791500 @default.
• W2152363872 cites W2058035594 @default.
• W2152363872 cites W2087793347 @default.
• W2152363872 cites W2090640084 @default.
• W2152363872 cites W2096162460 @default.
• W2152363872 cites W2096889454 @default.
• W2152363872 cites W2098126593 @default.
• W2152363872 cites W2101189906 @default.
• W2152363872 cites W2103170067 @default.
• W2152363872 cites W2104332925 @default.
• W2152363872 cites W2108018752 @default.
• W2152363872 cites W2111582999 @default.
• W2152363872 cites W2113265821 @default.
• W2152363872 cites W2115317782 @default.
• W2152363872 cites W2116596529 @default.
• W2152363872 cites W2117580564 @default.
• W2152363872 cites W2122071446 @default.
• W2152363872 cites W2126308420 @default.
• W2152363872 cites W2126568957 @default.
• W2152363872 cites W2128616554 @default.
• W2152363872 cites W2135721666 @default.
• W2152363872 cites W2141042406 @default.
• W2152363872 cites W2142392294 @default.
• W2152363872 cites W2145572561 @default.
• W2152363872 cites W2147932017 @default.
• W2152363872 cites W2149652290 @default.
• W2152363872 cites W2150884512 @default.
• W2152363872 cites W2153953403 @default.
• W2152363872 cites W2156887574 @default.
• W2152363872 cites W2158489424 @default.
• W2152363872 cites W2159367931 @default.
• W2152363872 cites W2161060487 @default.
• W2152363872 cites W2161865728 @default.
• W2152363872 cites W2163214563 @default.
• W2152363872 cites W2165822919 @default.
• W2152363872 cites W2166379983 @default.
• W2152363872 doi "https://doi.org/10.1371/journal.ppat.1000160" @default.
• W2152363872 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2528947" @default.
• W2152363872 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18802459" @default.
• W2152363872 hasPublicationYear "2008" @default.
• W2152363872 type Work @default.
• W2152363872 sameAs 2152363872 @default.
• W2152363872 citedByCount "396" @default.
• W2152363872 countsByYear W21523638722012 @default.
• W2152363872 countsByYear W21523638722013 @default.
• W2152363872 countsByYear W21523638722014 @default.
• W2152363872 countsByYear W21523638722015 @default.
• W2152363872 countsByYear W21523638722016 @default.
• W2152363872 countsByYear W21523638722017 @default.
• W2152363872 countsByYear W21523638722018 @default.
• W2152363872 countsByYear W21523638722019 @default.
• W2152363872 countsByYear W21523638722020 @default.
• W2152363872 countsByYear W21523638722021 @default.
• W2152363872 countsByYear W21523638722022 @default.
• W2152363872 countsByYear W21523638722023 @default.
• W2152363872 crossrefType "journal-article" @default.
• W2152363872 hasAuthorship W2152363872A5009745059 @default.
• W2152363872 hasAuthorship W2152363872A5009991935 @default.
• W2152363872 hasAuthorship W2152363872A5019583674 @default.
• W2152363872 hasAuthorship W2152363872A5025754154 @default.
• W2152363872 hasAuthorship W2152363872A5041529580 @default.
• W2152363872 hasAuthorship W2152363872A5043529126 @default.
• W2152363872 hasAuthorship W2152363872A5043828779 @default.
• W2152363872 hasAuthorship W2152363872A5050702223 @default.
• W2152363872 hasAuthorship W2152363872A5057991295 @default.
• W2152363872 hasAuthorship W2152363872A5063110744 @default.

• next