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• W2152416379 abstract "<h3>Background:</h3> The new technique of functional magnetic resonance imaging was used to investigate the mediating neuroanatomy of obsessive-compulsive disorder symptoms. <h3>Methods:</h3> Ten patients with obsessive-compulsive disorder and 5 normal subjects were studied via functional magnetic resonance imaging during control and provoked conditions. Data analysis entailed parametric and nonparametric statistical mapping. <h3>Results:</h3> Statistical maps (nonparametric;<i>P</i><10^-3) showed activation for 70% or more of patients with obsessive-compulsive disorder in medial orbitofrontal, lateral frontal, anterior temporal, anterior cingulate, and insular cortex, as well as caudate, lenticulate, and amygdala. No normal subjects exhibited activation in any brain region. <h3>Conclusions:</h3> Results of functional magnetic resonance imaging were consistent with past studies of obsessive-compulsive disorder that used other functional neuroimaging modalities. However, paralimbic and limbic activations were more prominent in the present study." @default.
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• W2152416379 date "1996-07-01" @default.
• W2152416379 modified "2023-10-16" @default.
• W2152416379 title "Functional Magnetic Resonance Imaging of Symptom Provocation in Obsessive-compulsive Disorder" @default.
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• W2152416379 doi "https://doi.org/10.1001/archpsyc.1996.01830070041008" @default.
• W2152416379 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8660126" @default.
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