FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2152448827> ?p ?o ?g. }

• W2152448827 endingPage "615" @default.
• W2152448827 startingPage "609" @default.
• W2152448827 abstract "The aim of this work was to study the effects of the nitric oxide synthase (NOS) inhibitors 7-n,troindazole (7-NI) and NG-nitro-L-arginine (L-NOARG) on the effects and pharmacokinetics of ethanol in rats. Ethanol at a dose of 4 g/kg, i.p. induced sleep in rats (sleep time: 117.2 ± 30.7 min). Administration of the NOS inhibitors 7-NI (20 mg/kg, i.p.) and L-NOARG (20 mg/kg, i.p.) 30 min before ethanol significantly increased the duration of ethanol-induced sleep. L-NOARG also significantly increased the toxicity of ethanol as evidenced by increased post-experimental lethality Ethanol at a dose of 2 g/kg (i.p.) did not induce sleep in vehicle-treated rats; however, the combined administration of ethanol (2 g/kg) and 7-NI at doses of 40, 80, and 120 mg/kg caused sleep, for 49.4 ± 3.7, 204.0 ± 13.3, and 447.5 ± 62.8 min, respectively. L-NOARG (20 mg/kg) had no effect on ethanol concentrations in blood after acute ethanol administration (4 g/kg). 7-NI in lower doses (20 and 40 mg/kg) had no effect and in higher doses (80 and 120 mg/kg) significantly slowed ethanol clearance during the 12 h after ethanol administration. The effect of 7-NI (20 mg/kg) on ethanol pharmacokinetics after chronic ethanol administration (inhalation for 18 days) was also studied. The administration of 7-NI immediately after the end of ethanol exposure had a pronounced effect on ethanol pharmacokinetics; in 7-NI-treated rats the fall in ethanol concentrations was significantly slower as compared with vehicle-treated rats. In 7-NI- treated rats, blood-ethanol levels were higher at 3, 6, 9, and 12 h after the end of ethanol exposure." @default.
• W2152448827 created "2016-06-24" @default.
• W2152448827 creator A5010480585 @default.
• W2152448827 creator A5013616853 @default.
• W2152448827 creator A5044846625 @default.
• W2152448827 creator A5066188338 @default.
• W2152448827 creator A5074361419 @default.
• W2152448827 date "1998-11-01" @default.
• W2152448827 modified "2023-09-27" @default.
• W2152448827 title "THE EFFECTS OF THE NITRIC OXIDE SYNTHASE INHIBITOR 7-NITROINDAZOLE ON ETHANOL PHARMACOKINETICS IN RATS AFTER ACUTE AND CHRONIC ETHANOL ADMINISTRATION" @default.
• W2152448827 cites W1955092925 @default.
• W2152448827 cites W1967705384 @default.
• W2152448827 cites W1971554191 @default.
• W2152448827 cites W1973534525 @default.
• W2152448827 cites W1976585673 @default.
• W2152448827 cites W1980849354 @default.
• W2152448827 cites W1990887160 @default.
• W2152448827 cites W1999740538 @default.
• W2152448827 cites W2000832826 @default.
• W2152448827 cites W2001593542 @default.
• W2152448827 cites W2004332163 @default.
• W2152448827 cites W2015050659 @default.
• W2152448827 cites W2015428986 @default.
• W2152448827 cites W2023207885 @default.
• W2152448827 cites W2027874257 @default.
• W2152448827 cites W2028763110 @default.
• W2152448827 cites W2031843542 @default.
• W2152448827 cites W2033625213 @default.
• W2152448827 cites W2035054078 @default.
• W2152448827 cites W2036631690 @default.
• W2152448827 cites W2036670338 @default.
• W2152448827 cites W2041931361 @default.
• W2152448827 cites W2048170615 @default.
• W2152448827 cites W2056321252 @default.
• W2152448827 cites W2062982587 @default.
• W2152448827 cites W2074449799 @default.
• W2152448827 cites W2082348521 @default.
• W2152448827 cites W2088962455 @default.
• W2152448827 cites W2091673079 @default.
• W2152448827 cites W2093708735 @default.
• W2152448827 cites W2133786574 @default.
• W2152448827 cites W2151160854 @default.
• W2152448827 cites W2416274292 @default.
• W2152448827 cites W3143411749 @default.
• W2152448827 cites W316854924 @default.
• W2152448827 cites W2397536154 @default.
• W2152448827 doi "https://doi.org/10.1093/alcalc/33.6.609" @default.
• W2152448827 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9872349" @default.
• W2152448827 hasPublicationYear "1998" @default.
• W2152448827 type Work @default.
• W2152448827 sameAs 2152448827 @default.
• W2152448827 citedByCount "13" @default.
• W2152448827 countsByYear W21524488272012 @default.
• W2152448827 countsByYear W21524488272013 @default.
• W2152448827 countsByYear W21524488272020 @default.
• W2152448827 crossrefType "journal-article" @default.
• W2152448827 hasAuthorship W2152448827A5010480585 @default.
• W2152448827 hasAuthorship W2152448827A5013616853 @default.
• W2152448827 hasAuthorship W2152448827A5044846625 @default.
• W2152448827 hasAuthorship W2152448827A5066188338 @default.
• W2152448827 hasAuthorship W2152448827A5074361419 @default.
• W2152448827 hasBestOaLocation W21524488271 @default.
• W2152448827 hasConcept C112705442 @default.
• W2152448827 hasConcept C178790620 @default.
• W2152448827 hasConcept C185592680 @default.
• W2152448827 hasConcept C2777622882 @default.
• W2152448827 hasConcept C2780161600 @default.
• W2152448827 hasConcept C29730261 @default.
• W2152448827 hasConcept C519581460 @default.
• W2152448827 hasConcept C55493867 @default.
• W2152448827 hasConcept C71924100 @default.
• W2152448827 hasConcept C98274493 @default.
• W2152448827 hasConceptScore W2152448827C112705442 @default.
• W2152448827 hasConceptScore W2152448827C178790620 @default.
• W2152448827 hasConceptScore W2152448827C185592680 @default.
• W2152448827 hasConceptScore W2152448827C2777622882 @default.
• W2152448827 hasConceptScore W2152448827C2780161600 @default.
• W2152448827 hasConceptScore W2152448827C29730261 @default.
• W2152448827 hasConceptScore W2152448827C519581460 @default.
• W2152448827 hasConceptScore W2152448827C55493867 @default.
• W2152448827 hasConceptScore W2152448827C71924100 @default.
• W2152448827 hasConceptScore W2152448827C98274493 @default.
• W2152448827 hasIssue "6" @default.
• W2152448827 hasLocation W21524488271 @default.
• W2152448827 hasLocation W21524488272 @default.
• W2152448827 hasOpenAccess W2152448827 @default.
• W2152448827 hasPrimaryLocation W21524488271 @default.
• W2152448827 hasRelatedWork W1990842025 @default.
• W2152448827 hasRelatedWork W1995586676 @default.
• W2152448827 hasRelatedWork W2033625213 @default.
• W2152448827 hasRelatedWork W2074424222 @default.
• W2152448827 hasRelatedWork W2082727219 @default.
• W2152448827 hasRelatedWork W2092007716 @default.
• W2152448827 hasRelatedWork W2323576217 @default.
• W2152448827 hasRelatedWork W2774225352 @default.
• W2152448827 hasRelatedWork W3080441546 @default.
• W2152448827 hasRelatedWork W4214585610 @default.
• W2152448827 hasVolume "33" @default.

• next