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- W2152496726 abstract "IL-13 is a cytokine known to play a role in several pulmonary diseases, including asthma and fibrosis. The role of IL-13 in the context of pulmonary changes induced by helminth infection is unclear. Rats experimentally infected with Strongyloides venezuelensis and treated with anti-IL-13 neutralizing antibody were used to evaluate the role of IL-13 on functional and inflammatory changes of host lungs, and on parasite control. S. venezuelensis-induced airway hyperreactivity was IL-13-independent, but IL-13 played an essential role in driving airway mucus production and eosinophil infiltration. IL-13 was important for the control of egg production but not establishment in the intestine." @default.
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- W2152496726 date "2010-05-01" @default.
- W2152496726 modified "2023-09-27" @default.
- W2152496726 title "Role of IL-13 in a model of Strongyloides venezuelensis infection in rats" @default.
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- W2152496726 doi "https://doi.org/10.1016/j.micinf.2010.01.012" @default.
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