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• W2152553357 abstract "The Acinetobacter baumannii 8399 clinical isolate secretes dihydroxybenzoic acid (DHBA) and a high-affinity catechol siderophore, which is different from other bacterial iron chelators already characterized. Complementation assays with enterobactin-deficient Escherichia coli strains led to the isolation of a cosmid clone containing A. baumannii 8399 genes required for the biosynthesis and activation of DHBA. Accordingly, the cloned fragment harbours a dhbACEB polycistronic operon encoding predicted proteins highly similar to several bacterial proteins required for DHBA biosynthesis from chorismic acid. Genes encoding deduced proteins related to the E. coli Fes and the Bacillus subtilis DhbF proteins, and a putative Yersinia pestis phosphopantetheinyl transferase, all of them involved in the assembly and utilization of catechol siderophores in other bacteria, were found next to the dhbACEB locus. This A. baumannii 8399 gene cluster also contained the om73, p45 and p114 predicted genes encoding proteins potentially involved in transport of ferric siderophore complexes. The deduced products of the p114 and p45 genes are putative membrane proteins that belong to the RND and MFS efflux pump proteins, respectively. Interestingly, P45 is highly related to the E. coli P43 (EntS) protein that participates in the secretion of enterobactin. Although P114 is similar to other bacterial efflux pump proteins involved in antibiotic resistance, its genetic arrangement within this A. baumannii 8399 locus is different from that described in other bacteria. The product of om73 is a Fur- and iron-regulated surface-exposed outer-membrane protein. These characteristics together with the presence of a predicted TonB box and its high similarity to other siderophore receptors indicate that OM73 plays such a role in A. baumannii 8399. The 184 nt om73-p114 intergenic region contains promoter elements that could drive the expression of these divergently transcribed genes, all of which are in close proximity to almost perfect Fur boxes. This arrangement explains the iron- and Fur-regulated expression of om73, and provides strong evidence for a similar regulation for the expression of p114." @default.
• W2152553357 created "2016-06-24" @default.
• W2152553357 creator A5001662452 @default.
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• W2152553357 creator A5040132475 @default.
• W2152553357 creator A5091878259 @default.
• W2152553357 date "2003-05-01" @default.
• W2152553357 modified "2023-10-03" @default.
• W2152553357 title "Genetic organization of an Acinetobacter baumannii chromosomal region harbouring genes related to siderophore biosynthesis and transport" @default.
• W2152553357 cites W1491955340 @default.
• W2152553357 cites W1510702873 @default.
• W2152553357 cites W1511168381 @default.
• W2152553357 cites W1530687839 @default.
• W2152553357 cites W1545319228 @default.
• W2152553357 cites W1546975573 @default.
• W2152553357 cites W1548845294 @default.
• W2152553357 cites W1556994095 @default.
• W2152553357 cites W1566845757 @default.
• W2152553357 cites W1567229835 @default.
• W2152553357 cites W1587329961 @default.
• W2152553357 cites W1599109452 @default.
• W2152553357 cites W1603707660 @default.
• W2152553357 cites W1669205909 @default.
• W2152553357 cites W1785725253 @default.
• W2152553357 cites W1810566039 @default.
• W2152553357 cites W1821933068 @default.
• W2152553357 cites W1849522036 @default.
• W2152553357 cites W1873199501 @default.
• W2152553357 cites W1960351290 @default.
• W2152553357 cites W1975954203 @default.
• W2152553357 cites W1983790046 @default.
• W2152553357 cites W1987998614 @default.
• W2152553357 cites W2005091504 @default.
• W2152553357 cites W2006548681 @default.
• W2152553357 cites W2007590707 @default.
• W2152553357 cites W2009608644 @default.
• W2152553357 cites W2013740990 @default.
• W2152553357 cites W2014669590 @default.
• W2152553357 cites W2018396914 @default.
• W2152553357 cites W2019410656 @default.
• W2152553357 cites W2021088239 @default.
• W2152553357 cites W2023229596 @default.
• W2152553357 cites W2029523115 @default.
• W2152553357 cites W2049279213 @default.
• W2152553357 cites W2050499271 @default.
• W2152553357 cites W2058264922 @default.
• W2152553357 cites W2063212075 @default.
• W2152553357 cites W2066369481 @default.
• W2152553357 cites W2068518785 @default.
• W2152553357 cites W2069036586 @default.
• W2152553357 cites W2074778021 @default.
• W2152553357 cites W2082602326 @default.
• W2152553357 cites W2093085944 @default.
• W2152553357 cites W2095617611 @default.
• W2152553357 cites W2103557492 @default.
• W2152553357 cites W2106311846 @default.
• W2152553357 cites W2107656569 @default.
• W2152553357 cites W2110256580 @default.
• W2152553357 cites W2112160620 @default.
• W2152553357 cites W2116513121 @default.
• W2152553357 cites W2120171067 @default.
• W2152553357 cites W2124343952 @default.
• W2152553357 cites W2125187809 @default.
• W2152553357 cites W2128022667 @default.
• W2152553357 cites W2134615708 @default.
• W2152553357 cites W2135164300 @default.
• W2152553357 cites W2145874353 @default.
• W2152553357 cites W2149353640 @default.
• W2152553357 cites W2154414887 @default.
• W2152553357 cites W2156299366 @default.
• W2152553357 cites W2159648425 @default.
• W2152553357 cites W2172046337 @default.
• W2152553357 cites W2180864382 @default.
• W2152553357 cites W2231437427 @default.
• W2152553357 cites W2393644118 @default.
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• W2152553357 cites W4245782087 @default.
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• W2152553357 doi "https://doi.org/10.1099/mic.0.26204-0" @default.
• W2152553357 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12724384" @default.
• W2152553357 hasPublicationYear "2003" @default.
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