FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2152636722> ?p ?o ?g. }

• W2152636722 endingPage "26" @default.
• W2152636722 startingPage "21" @default.
• W2152636722 abstract "Since it has been considered that suppression of spontaneous mutation in cells is related to suppression of spontaneous carcinogenesis, it is significant to detect substances which suppress spontaneous mutation in bacterial cells such as Escherichia coli and Salmonella typhimurium in the environment. However, since the frequency of spontaneous mutation in bacteria is usually very low, generally 10(-8)-10(-10),it is difficult to determine significant suppressive ability of such substances on spontaneous mutation. A new method, Mut-Test, was developed by us, applying Luria & Delbruck fluctuation test, to detect substances which suppress spontaneous mutation using E. coli mutT mutant in which spontaneous mutation frequency due to oxidative damage is enhanced to approximately 500-1000 times of the wild type strain. Suppressive abilities of two hydroxyl radical scavengers: D(-)-mannitol and thiourea, were examined and clear positive results were obtained, suggesting that the radical scavengers are suitable as the positive control for the test. Using Mut-Test, suppressive abilities of four vitamins: L-ascorbic acid, beta-carotene, folic acid and riboflavin; 10 polyphenols: caffeic acid, ellagic acid, (-)-epicatechin, (-)-epicatechin gallate, (-)-epigallocatechin, gallic acid, pyrocatechol, pyrogallol, quercetin and tannic acid which are recognized as antimutagens, were examined. Furthermore, the concentrations for 50% of suppressive abilities of five positive samples, L-ascorbic acid, folic acid, caffeic acid, pyrocatechol and pyrogallol were compared. Negative results were obtained in nine samples, riboflavin, tannic acid, etc. suggesting that their antimutagenic effect on cells may not be related to oxidative damage in cells." @default.
• W2152636722 created "2016-06-24" @default.
• W2152636722 creator A5012140616 @default.
• W2152636722 creator A5021209820 @default.
• W2152636722 creator A5062007096 @default.
• W2152636722 creator A5089345377 @default.
• W2152636722 date "2001-01-01" @default.
• W2152636722 modified "2023-10-13" @default.
• W2152636722 title "Mut-Test to detect substances suppressing spontaneous mutation due to oxidative damage" @default.
• W2152636722 cites W1828771602 @default.
• W2152636722 cites W1849997836 @default.
• W2152636722 cites W1966781584 @default.
• W2152636722 cites W1969842031 @default.
• W2152636722 cites W1970473268 @default.
• W2152636722 cites W1986168521 @default.
• W2152636722 cites W1995679932 @default.
• W2152636722 cites W2004502338 @default.
• W2152636722 cites W2011804819 @default.
• W2152636722 cites W2012979846 @default.
• W2152636722 cites W2015387809 @default.
• W2152636722 cites W2028622989 @default.
• W2152636722 cites W2035595729 @default.
• W2152636722 cites W2043268620 @default.
• W2152636722 cites W2052429166 @default.
• W2152636722 cites W2058395401 @default.
• W2152636722 cites W2061590657 @default.
• W2152636722 cites W2063062911 @default.
• W2152636722 cites W2063450941 @default.
• W2152636722 cites W2077764388 @default.
• W2152636722 cites W2091024112 @default.
• W2152636722 cites W2092130692 @default.
• W2152636722 cites W2149137963 @default.
• W2152636722 cites W2161524167 @default.
• W2152636722 cites W2161604841 @default.
• W2152636722 cites W2165229464 @default.
• W2152636722 cites W2170343590 @default.
• W2152636722 cites W2319757645 @default.
• W2152636722 cites W4246461721 @default.
• W2152636722 doi "https://doi.org/10.1016/s1383-5718(00)00148-0" @default.
• W2152636722 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11152968" @default.
• W2152636722 hasPublicationYear "2001" @default.
• W2152636722 type Work @default.
• W2152636722 sameAs 2152636722 @default.
• W2152636722 citedByCount "10" @default.
• W2152636722 countsByYear W21526367222013 @default.
• W2152636722 crossrefType "journal-article" @default.
• W2152636722 hasAuthorship W2152636722A5012140616 @default.
• W2152636722 hasAuthorship W2152636722A5021209820 @default.
• W2152636722 hasAuthorship W2152636722A5062007096 @default.
• W2152636722 hasAuthorship W2152636722A5089345377 @default.
• W2152636722 hasConcept C102306862 @default.
• W2152636722 hasConcept C104317684 @default.
• W2152636722 hasConcept C143065580 @default.
• W2152636722 hasConcept C178790620 @default.
• W2152636722 hasConcept C185592680 @default.
• W2152636722 hasConcept C2776344562 @default.
• W2152636722 hasConcept C2778004101 @default.
• W2152636722 hasConcept C2778224086 @default.
• W2152636722 hasConcept C2778362808 @default.
• W2152636722 hasConcept C2781393965 @default.
• W2152636722 hasConcept C2781464872 @default.
• W2152636722 hasConcept C2986274086 @default.
• W2152636722 hasConcept C31903555 @default.
• W2152636722 hasConcept C55493867 @default.
• W2152636722 hasConcept C70899900 @default.
• W2152636722 hasConceptScore W2152636722C102306862 @default.
• W2152636722 hasConceptScore W2152636722C104317684 @default.
• W2152636722 hasConceptScore W2152636722C143065580 @default.
• W2152636722 hasConceptScore W2152636722C178790620 @default.
• W2152636722 hasConceptScore W2152636722C185592680 @default.
• W2152636722 hasConceptScore W2152636722C2776344562 @default.
• W2152636722 hasConceptScore W2152636722C2778004101 @default.
• W2152636722 hasConceptScore W2152636722C2778224086 @default.
• W2152636722 hasConceptScore W2152636722C2778362808 @default.
• W2152636722 hasConceptScore W2152636722C2781393965 @default.
• W2152636722 hasConceptScore W2152636722C2781464872 @default.
• W2152636722 hasConceptScore W2152636722C2986274086 @default.
• W2152636722 hasConceptScore W2152636722C31903555 @default.
• W2152636722 hasConceptScore W2152636722C55493867 @default.
• W2152636722 hasConceptScore W2152636722C70899900 @default.
• W2152636722 hasIssue "1" @default.
• W2152636722 hasLocation W21526367221 @default.
• W2152636722 hasLocation W21526367222 @default.
• W2152636722 hasOpenAccess W2152636722 @default.
• W2152636722 hasPrimaryLocation W21526367221 @default.
• W2152636722 hasRelatedWork W2024090346 @default.
• W2152636722 hasRelatedWork W2052759292 @default.
• W2152636722 hasRelatedWork W2066587021 @default.
• W2152636722 hasRelatedWork W2327156579 @default.
• W2152636722 hasRelatedWork W2366787677 @default.
• W2152636722 hasRelatedWork W2465177422 @default.
• W2152636722 hasRelatedWork W3030089684 @default.
• W2152636722 hasRelatedWork W3098874497 @default.
• W2152636722 hasRelatedWork W3168001404 @default.
• W2152636722 hasRelatedWork W4296439452 @default.
• W2152636722 hasVolume "490" @default.
• W2152636722 isParatext "false" @default.
• W2152636722 isRetracted "false" @default.

• next