Matches in SemOpenAlex for { <https://semopenalex.org/work/W2152664900> ?p ?o ?g. }
- W2152664900 abstract "Ebola virus (EBOV) is a filamentous negative-strand RNA virus with a glycoprotein envelope and comprises four species, Zaire, Sudan, Ivory Coast and Reston. It is a highly lethal pathogen for humans as well as non-human primates, and has been responsible for numerous African epidemics of viral hemorrhagic fever over the past 29 years. There is also concern that EBOV might be used as an aerosol-transmitted bioterrorism agent. The syndrome of Ebola hemorrhagic fever (EHF) is a paradigm of multiorgan dysfunction characterized by a macular rash, disseminated intravascular coagulopathy (DIC), severe lymphocyte apoptosis, profound hypotension and a failed adaptive immune response to EBOV. Pathogenetic studies in non-human primates have shown that EHF stems from early EBOV infection of dendritic cells and that the DIC is associated with up-regulated tissue factor expression in EBOV-infected monocytes/macrophages and on microparticles released from these cells. Although there is no efficacious antiviral treatment..." @default.
- W2152664900 created "2016-06-24" @default.
- W2152664900 creator A5076130470 @default.
- W2152664900 date "2005-01-01" @default.
- W2152664900 modified "2023-10-16" @default.
- W2152664900 title "Ebola hemorrhagic fever: a paradigm of multiorgan dysfunction" @default.
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- W2152664900 doi "https://doi.org/10.1080/14764170500223456" @default.