Matches in SemOpenAlex for { <https://semopenalex.org/work/W2152679247> ?p ?o ?g. }
Showing items 1 to 90 of
90
with 100 items per page.
- W2152679247 endingPage "283" @default.
- W2152679247 startingPage "275" @default.
- W2152679247 abstract "Using a panel of anti-CD3-TCR monoclonal antibodies (OKT3 A-E), it appears possible to separate the ability to cause surface antigen modulation from inhibition of MLR or induction of mitosis. OKT3D, an antibody that recognizes the CD3 antigen at a site that can be differentiated from the epitopes recognized by other members of this panel by competition binding, does not cause antigen modulation when incubated with human T cells for up to 3 days. Despite this, OKT3D is mitogenic and is capable of blocking MLR. Two different isotypes were produced from the OKT3D clone, IgG1 and IgG2b. The IgG2b isotype of OKT3D blocked MLR even in individuals unable to respond mitogenically to this antibody. Use of members of this panel may now permit dissection of the types of signals delivered by the CD3-TCR complex inducing mitosis, receptor modulation, and other T-cell responses." @default.
- W2152679247 created "2016-06-24" @default.
- W2152679247 creator A5017348288 @default.
- W2152679247 creator A5037230570 @default.
- W2152679247 creator A5047908852 @default.
- W2152679247 creator A5066506062 @default.
- W2152679247 creator A5072296544 @default.
- W2152679247 creator A5085800754 @default.
- W2152679247 date "1992-04-01" @default.
- W2152679247 modified "2023-09-27" @default.
- W2152679247 title "Identification of anti-CD3 antibodies that do not modulate antigen but induce mitogenesis and block the mixed lymphocyte reaction" @default.
- W2152679247 cites W1963969128 @default.
- W2152679247 cites W1964622046 @default.
- W2152679247 cites W2004106131 @default.
- W2152679247 cites W2040503220 @default.
- W2152679247 cites W2054008992 @default.
- W2152679247 cites W2100837269 @default.
- W2152679247 cites W2108391599 @default.
- W2152679247 cites W2111321496 @default.
- W2152679247 doi "https://doi.org/10.1016/0198-8859(92)90335-k" @default.
- W2152679247 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1386354" @default.
- W2152679247 hasPublicationYear "1992" @default.
- W2152679247 type Work @default.
- W2152679247 sameAs 2152679247 @default.
- W2152679247 citedByCount "3" @default.
- W2152679247 crossrefType "journal-article" @default.
- W2152679247 hasAuthorship W2152679247A5017348288 @default.
- W2152679247 hasAuthorship W2152679247A5037230570 @default.
- W2152679247 hasAuthorship W2152679247A5047908852 @default.
- W2152679247 hasAuthorship W2152679247A5066506062 @default.
- W2152679247 hasAuthorship W2152679247A5072296544 @default.
- W2152679247 hasAuthorship W2152679247A5085800754 @default.
- W2152679247 hasConcept C114684123 @default.
- W2152679247 hasConcept C147483822 @default.
- W2152679247 hasConcept C153911025 @default.
- W2152679247 hasConcept C159654299 @default.
- W2152679247 hasConcept C167672396 @default.
- W2152679247 hasConcept C19317047 @default.
- W2152679247 hasConcept C195616568 @default.
- W2152679247 hasConcept C203014093 @default.
- W2152679247 hasConcept C2776090121 @default.
- W2152679247 hasConcept C2777991845 @default.
- W2152679247 hasConcept C2778740727 @default.
- W2152679247 hasConcept C2992881475 @default.
- W2152679247 hasConcept C542903549 @default.
- W2152679247 hasConcept C552990157 @default.
- W2152679247 hasConcept C55493867 @default.
- W2152679247 hasConcept C81089528 @default.
- W2152679247 hasConcept C86803240 @default.
- W2152679247 hasConcept C8891405 @default.
- W2152679247 hasConceptScore W2152679247C114684123 @default.
- W2152679247 hasConceptScore W2152679247C147483822 @default.
- W2152679247 hasConceptScore W2152679247C153911025 @default.
- W2152679247 hasConceptScore W2152679247C159654299 @default.
- W2152679247 hasConceptScore W2152679247C167672396 @default.
- W2152679247 hasConceptScore W2152679247C19317047 @default.
- W2152679247 hasConceptScore W2152679247C195616568 @default.
- W2152679247 hasConceptScore W2152679247C203014093 @default.
- W2152679247 hasConceptScore W2152679247C2776090121 @default.
- W2152679247 hasConceptScore W2152679247C2777991845 @default.
- W2152679247 hasConceptScore W2152679247C2778740727 @default.
- W2152679247 hasConceptScore W2152679247C2992881475 @default.
- W2152679247 hasConceptScore W2152679247C542903549 @default.
- W2152679247 hasConceptScore W2152679247C552990157 @default.
- W2152679247 hasConceptScore W2152679247C55493867 @default.
- W2152679247 hasConceptScore W2152679247C81089528 @default.
- W2152679247 hasConceptScore W2152679247C86803240 @default.
- W2152679247 hasConceptScore W2152679247C8891405 @default.
- W2152679247 hasIssue "4" @default.
- W2152679247 hasLocation W21526792471 @default.
- W2152679247 hasLocation W21526792472 @default.
- W2152679247 hasOpenAccess W2152679247 @default.
- W2152679247 hasPrimaryLocation W21526792471 @default.
- W2152679247 hasRelatedWork W1605454818 @default.
- W2152679247 hasRelatedWork W1969516523 @default.
- W2152679247 hasRelatedWork W2003301929 @default.
- W2152679247 hasRelatedWork W2009889818 @default.
- W2152679247 hasRelatedWork W2016026615 @default.
- W2152679247 hasRelatedWork W2057436540 @default.
- W2152679247 hasRelatedWork W2069971243 @default.
- W2152679247 hasRelatedWork W2110363972 @default.
- W2152679247 hasRelatedWork W2147986256 @default.
- W2152679247 hasRelatedWork W2152679247 @default.
- W2152679247 hasVolume "33" @default.
- W2152679247 isParatext "false" @default.
- W2152679247 isRetracted "false" @default.
- W2152679247 magId "2152679247" @default.
- W2152679247 workType "article" @default.