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- W2152707386 abstract "Historically, patients ≥40 years of age treated for infertility with IVF have diminished results due to rising FSH levels, poor recruitment of follicles and low response to ovulation induction. Recovery of oocytes have customarily been few and of poor quality. Due to the recent availability and improvement of sequential culture medium for IVF, we wanted to examine the possibility of taking the resulting embryos from these patients out to day 6 (blastocyst stage) to see if these fully developed embryos would have an impact on pregnancy rates. This was a retrospective analysis. 29 patients, ≥40 years of age treated with IVF and subsequent embryo transfer from November 2002 to September 2003 were entered into the study based on the presence of 6 or more “A” quality embryos on day 2 of embryo development. Patients received either 2 or 3 embryos at transfer. Out of the 29 patients that participated in the study, the average age was 41.8 and the average FSH level was 7.45. All 29 patients went to egg retrieval with an average of 12.4 eggs per patient with an average of 3 of those eggs making it to blastocyst. A positive pregnancy test was observed in 20 patients for a 68.9% pregnancy rate. We conclude that in our study of patients ≥40 years of age, IVF, the day 2 selection criteria, and the use of sequential culture medium can be used to greatly improve the quality of embryos and pregnancy rates in this patient population." @default.
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- W2152707386 date "2004-09-01" @default.
- W2152707386 modified "2023-09-27" @default.
- W2152707386 title "A retrospective analysis: Culture and transfer of day 6 human blastocysts increases pregnancy rates in patients over 40 years old" @default.
- W2152707386 doi "https://doi.org/10.1016/j.fertnstert.2004.07.874" @default.
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