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• W2152763316 startingPage "447" @default.
• W2152763316 abstract "Abstract Fourteen novel single-amino-acid substitution mutations in histone H3 that disrupt telomeric silencing in Saccharomyces cerevisiae were identified, 10 of which are clustered within the α1 helix and L1 loop of the essential histone fold. Several of these mutations cause derepression of silent mating locus HML, and an additional subset cause partial loss of basal repression at the GAL1 promoter. Our results identify a new domain within the essential core of histone H3 that is required for heterochromatin-mediated silencing." @default.
• W2152763316 created "2016-06-24" @default.
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• W2152763316 date "2003-01-01" @default.
• W2152763316 modified "2023-09-26" @default.
• W2152763316 title "Identification of a Functional Domain Within the Essential Core of Histone H3 That Is Required for Telomeric and <i>HM</i> Silencing in <i>Saccharomyces cerevisiae</i>" @default.
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• W2152763316 doi "https://doi.org/10.1093/genetics/163.1.447" @default.
• W2152763316 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1462409" @default.
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