FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2152804549> ?p ?o ?g. }

• W2152804549 endingPage "1490" @default.
• W2152804549 startingPage "1481" @default.
• W2152804549 abstract "Do in vitro fertilization (IVF) multiples generate higher hospital costs than IVF singletons, from birth up to age 5? Hospital costs from birth up to age 5 were significantly higher among IVF/ICSI multiple children compared with IVF/ICSI singletons; however, when excluding the costs incurred during the birth admission period, hospital costs of multiples and singletons were comparable. Concern has risen over the long-term outcome of children born after IVF. The increased incidence of multiple births in IVF as a result of double-embryo transfer predisposes children to a poorer neonatal outcome such as preterm birth and low birthweight. As a consequence, IVF multiples require more medical care. Costs and consequences of poorer neonatal outcomes in multiples may also exist later in life. All 5497 children born from IVF in 2003–2005, whose parents received IVF or ICSI treatment in one of five participating Dutch IVF centers, served as a basis for a retrospective cohort study. Based on gestational age, birthweight, Apgar and congenital malformation, children were assigned to one of three risk strata (low-, moderate- or high-risk). To enhance the efficiency of the data collection, 816 multiples and 584 singletons were selected for 5-year follow-up based on stratified (risk) sampling. Parental informed consent was received of 322 multiples and 293 singletons. Individual-level hospital resource use data (hospitalization, outpatient visits and medical procedures) were retrieved from hospital information systems and patient charts for 302 multiples and 278 singletons. The risk of hospitalization (OR 4.9, 95% CI 3.3–7.0), outpatient visits (OR 2.6, 95% CI 1.8–3.6) and medical procedures (OR 1.7, 95% CI 1.2–2.2) was higher for multiples compared with singletons. The average hospital costs amounted to €10 018 and €2093 during the birth admission period (P < 0.001), €1131 and €696 after the birth admission period to the first birthday (not significant (n.s.)) and €1084 and €938 from the second to the fifth life year (n.s.) for multiples and singletons, respectively. Hospital costs from birth up to age 5 were 3.3-fold higher for multiples compared with singletons (P < 0.001). Among multiples and singletons, respectively, 90.8 and 76.2% of the total hospital costs were caused by hospital admission days and 8.9 and 25.2% of the total hospital costs during the first 5 years of life occurred after the first year of life. Resource use and costs outside the hospital were not included in the analysis. This study confirms the increased use of healthcare resources by IVF/ICSI multiples compared with IVF/ICSI singletons. Single-embryo transfer may result in substantial savings, particularly in the birth admission period. These savings need to be compared with the extra costs of additional embryo transfers needed to achieve a successful pregnancy. Besides costs, health outcomes of children born after single-embryo transfer should be compared with those born after double-embryo transfer. This study was supported by a research grant (grant number 80-82310-98-09094) from the Netherlands Organization for Health Research and Development (ZonMw). There are no conflicts of interest in connection with this article. Not applicable." @default.
• W2152804549 created "2016-06-24" @default.
• W2152804549 creator A5004759960 @default.
• W2152804549 creator A5030513453 @default.
• W2152804549 creator A5032868345 @default.
• W2152804549 creator A5035773850 @default.
• W2152804549 creator A5055643997 @default.
• W2152804549 creator A5057319844 @default.
• W2152804549 creator A5062131691 @default.
• W2152804549 creator A5064153691 @default.
• W2152804549 creator A5066282670 @default.
• W2152804549 creator A5067211712 @default.
• W2152804549 creator A5071724912 @default.
• W2152804549 creator A5078814393 @default.
• W2152804549 creator A5084681961 @default.
• W2152804549 creator A5085459795 @default.
• W2152804549 creator A5089870658 @default.
• W2152804549 date "2015-04-02" @default.
• W2152804549 modified "2023-10-11" @default.
• W2152804549 title "Hospital costs during the first 5 years of life for multiples compared with singletons born after IVF or ICSI" @default.
• W2152804549 cites W1967935846 @default.
• W2152804549 cites W1978816587 @default.
• W2152804549 cites W1989464632 @default.
• W2152804549 cites W1991228187 @default.
• W2152804549 cites W2003670543 @default.
• W2152804549 cites W2007462750 @default.
• W2152804549 cites W2015426272 @default.
• W2152804549 cites W2020169059 @default.
• W2152804549 cites W2044401165 @default.
• W2152804549 cites W2056466426 @default.
• W2152804549 cites W2085500544 @default.
• W2152804549 cites W2086820557 @default.
• W2152804549 cites W2088894206 @default.
• W2152804549 cites W2090757502 @default.
• W2152804549 cites W2094523683 @default.
• W2152804549 cites W2096526005 @default.
• W2152804549 cites W2110211081 @default.
• W2152804549 cites W2110373085 @default.
• W2152804549 cites W2121929246 @default.
• W2152804549 cites W2128991285 @default.
• W2152804549 cites W2143761821 @default.
• W2152804549 cites W2144618630 @default.
• W2152804549 cites W2145647914 @default.
• W2152804549 cites W2147575721 @default.
• W2152804549 cites W2153305701 @default.
• W2152804549 cites W2153573704 @default.
• W2152804549 cites W2162482134 @default.
• W2152804549 cites W2166195927 @default.
• W2152804549 doi "https://doi.org/10.1093/humrep/dev059" @default.
• W2152804549 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25840426" @default.
• W2152804549 hasPublicationYear "2015" @default.
• W2152804549 type Work @default.
• W2152804549 sameAs 2152804549 @default.
• W2152804549 citedByCount "19" @default.
• W2152804549 countsByYear W21528045492015 @default.
• W2152804549 countsByYear W21528045492016 @default.
• W2152804549 countsByYear W21528045492017 @default.
• W2152804549 countsByYear W21528045492018 @default.
• W2152804549 countsByYear W21528045492020 @default.
• W2152804549 countsByYear W21528045492021 @default.
• W2152804549 countsByYear W21528045492022 @default.
• W2152804549 crossrefType "journal-article" @default.
• W2152804549 hasAuthorship W2152804549A5004759960 @default.
• W2152804549 hasAuthorship W2152804549A5030513453 @default.
• W2152804549 hasAuthorship W2152804549A5032868345 @default.
• W2152804549 hasAuthorship W2152804549A5035773850 @default.
• W2152804549 hasAuthorship W2152804549A5055643997 @default.
• W2152804549 hasAuthorship W2152804549A5057319844 @default.
• W2152804549 hasAuthorship W2152804549A5062131691 @default.
• W2152804549 hasAuthorship W2152804549A5064153691 @default.
• W2152804549 hasAuthorship W2152804549A5066282670 @default.
• W2152804549 hasAuthorship W2152804549A5067211712 @default.
• W2152804549 hasAuthorship W2152804549A5071724912 @default.
• W2152804549 hasAuthorship W2152804549A5078814393 @default.
• W2152804549 hasAuthorship W2152804549A5084681961 @default.
• W2152804549 hasAuthorship W2152804549A5085459795 @default.
• W2152804549 hasAuthorship W2152804549A5089870658 @default.
• W2152804549 hasConcept C120665830 @default.
• W2152804549 hasConcept C121332964 @default.
• W2152804549 hasConcept C126322002 @default.
• W2152804549 hasConcept C131872663 @default.
• W2152804549 hasConcept C167135981 @default.
• W2152804549 hasConcept C187212893 @default.
• W2152804549 hasConcept C2778279030 @default.
• W2152804549 hasConcept C2778376644 @default.
• W2152804549 hasConcept C2779234561 @default.
• W2152804549 hasConcept C2779755304 @default.
• W2152804549 hasConcept C2780340734 @default.
• W2152804549 hasConcept C2908647359 @default.
• W2152804549 hasConcept C29456083 @default.
• W2152804549 hasConcept C518429986 @default.
• W2152804549 hasConcept C54355233 @default.
• W2152804549 hasConcept C61511704 @default.
• W2152804549 hasConcept C71924100 @default.
• W2152804549 hasConcept C86803240 @default.
• W2152804549 hasConcept C99454951 @default.
• W2152804549 hasConceptScore W2152804549C120665830 @default.
• W2152804549 hasConceptScore W2152804549C121332964 @default.

• next