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- W2152842009 abstract "Heterocycles have been modified in various ways in the search for new functions, but few examples are known of crown ethers incorporating heterocycles in macro-ring systems. Here we report a simple and versatile synthesis of crown ether-bearing heterocycles. An acylurea moiety in the heterocycles is efficiently transformed to 'crown ether' of various ring sizes. The products included a Ca(2+)-selective fluoroionophore. Our simple methodology is expected to provide many novel functional heterocyclic compounds, including fluoroionophores and candidate pharmaceuticals." @default.
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- W2152842009 date "2007-11-01" @default.
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- W2152842009 title "A versatile strategy for the synthesis of crown ether-bearing heterocycles: Discovery of calcium-selective fluoroionophore" @default.
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- W2152842009 doi "https://doi.org/10.1016/j.bmc.2007.07.035" @default.
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