Matches in SemOpenAlex for { <https://semopenalex.org/work/W2152898032> ?p ?o ?g. }
- W2152898032 endingPage "533" @default.
- W2152898032 startingPage "526" @default.
- W2152898032 abstract "The purpose of this paper is to report a case of fluoride poisoning along with a discussion of poisoning characteristics, analytical procedures, and a review of previous reports of fatal intoxications with analytical data. A case of suicidal ingestion of 40 mL of a rust removal agent containing hydrofluoric acid and ammonium fluoride by a 33-year-old white male is presented. He had an organic personality disorder with residual schizophrenia and previous suicide attempts with therapeutic drugs and cleaning products. At admission, he presented with a Glasgow coma score of 3, third degree atrioventricular block, and asystole. Resuscitation efforts were performed during which the patient suffered two episodes of ventricular fibrillation followed by asystole. In spite of advanced resuscitation efforts and the administration of calcium chloride, he died 2.5 h after the ingestion. Analytical data in the hospital showed calcium levels of 3.1 mg/dL and metabolic acidosis. Internal findings were erosive gastritis, brain edema, and pulmonary and hepatic congestion. Quantitation of fluoride was performed using an ion-selective electrode for the anion. Disposition of fluoride in the different tissues was as follows: peripheral blood, 19.4 mg/L; urine, 670 mg/L; vitreous humor, 2.5 mg/L; liver, 40.0 mg/kg; kidney, 60.0 mg/kg; lung, 17.5 mg/kg; brain, 2.5 mg/kg; spleen, 30.0 mg/kg; bone, 0.5 mg/ kg; and gastric content, 1120 mg/L (67 mg total). Validation of the analytical method was performed using different spiked tissues, in a range of concentrations from 2.4 to 475 mg/L or mg/kg, and submitting them to dilution (1:25) to avoid the matrix effect and to bring these concentrations to the range of the aqueous calibration curve (0.19-19 mg/L). Limits of detection and quantitation were 0.02 and 0.1 mg/L, respectively. The linearity of the method, for all studies tissues, was excellent, with r(2) values of 0.999. Accuracy and precision were within 10.5% and 5.7%, respectively. Fluoride analyses using the ion selective electrode are simple, sensitive, and rapid. This report provides an extensive tissue distribution study of fluoride after a well documented case of acute poisoning. Based on the autopsy findings, patient history, toxicology results, and previously reported data the forensic pathologists ruled that the cause of death was due to a fluoride poisoning, and the manner of death was listed as suicide." @default.
- W2152898032 created "2016-06-24" @default.
- W2152898032 creator A5029680972 @default.
- W2152898032 creator A5041887666 @default.
- W2152898032 creator A5056680330 @default.
- W2152898032 creator A5060861919 @default.
- W2152898032 creator A5079595950 @default.
- W2152898032 date "2007-10-01" @default.
- W2152898032 modified "2023-10-16" @default.
- W2152898032 title "The Tissue Distribution of Fluoride in a Fatal Case of Self-Poisoning" @default.
- W2152898032 cites W1581990460 @default.
- W2152898032 cites W1971354371 @default.
- W2152898032 cites W1974397344 @default.
- W2152898032 cites W1974513717 @default.
- W2152898032 cites W1991430445 @default.
- W2152898032 cites W2000007411 @default.
- W2152898032 cites W2010113888 @default.
- W2152898032 cites W2011926816 @default.
- W2152898032 cites W2015094756 @default.
- W2152898032 cites W2015240056 @default.
- W2152898032 cites W2033037694 @default.
- W2152898032 cites W2035134095 @default.
- W2152898032 cites W2036307499 @default.
- W2152898032 cites W2044131966 @default.
- W2152898032 cites W2044389094 @default.
- W2152898032 cites W2045177955 @default.
- W2152898032 cites W2065430797 @default.
- W2152898032 cites W2065760719 @default.
- W2152898032 cites W2074524822 @default.
- W2152898032 cites W2079114295 @default.
- W2152898032 cites W2079520885 @default.
- W2152898032 cites W2080417974 @default.
- W2152898032 cites W2081227076 @default.
- W2152898032 cites W2085048394 @default.
- W2152898032 cites W2087058598 @default.
- W2152898032 cites W209693059 @default.
- W2152898032 cites W2110552301 @default.
- W2152898032 cites W2112510980 @default.
- W2152898032 cites W2113999907 @default.
- W2152898032 cites W2147832489 @default.
- W2152898032 cites W2156768784 @default.
- W2152898032 cites W2159461253 @default.
- W2152898032 cites W2164641501 @default.
- W2152898032 cites W2281117918 @default.
- W2152898032 cites W2285423437 @default.
- W2152898032 cites W2315833978 @default.
- W2152898032 cites W2329376561 @default.
- W2152898032 cites W2440081772 @default.
- W2152898032 cites W2895087986 @default.
- W2152898032 cites W62486391 @default.
- W2152898032 cites W2240641249 @default.
- W2152898032 doi "https://doi.org/10.1093/jat/31.8.526" @default.
- W2152898032 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17988468" @default.
- W2152898032 hasPublicationYear "2007" @default.
- W2152898032 type Work @default.
- W2152898032 sameAs 2152898032 @default.
- W2152898032 citedByCount "12" @default.
- W2152898032 countsByYear W21528980322014 @default.
- W2152898032 countsByYear W21528980322015 @default.
- W2152898032 countsByYear W21528980322016 @default.
- W2152898032 countsByYear W21528980322018 @default.
- W2152898032 countsByYear W21528980322019 @default.
- W2152898032 countsByYear W21528980322021 @default.
- W2152898032 countsByYear W21528980322022 @default.
- W2152898032 crossrefType "journal-article" @default.
- W2152898032 hasAuthorship W2152898032A5029680972 @default.
- W2152898032 hasAuthorship W2152898032A5041887666 @default.
- W2152898032 hasAuthorship W2152898032A5056680330 @default.
- W2152898032 hasAuthorship W2152898032A5060861919 @default.
- W2152898032 hasAuthorship W2152898032A5079595950 @default.
- W2152898032 hasBestOaLocation W21528980321 @default.
- W2152898032 hasConcept C100136789 @default.
- W2152898032 hasConcept C120665830 @default.
- W2152898032 hasConcept C121332964 @default.
- W2152898032 hasConcept C126322002 @default.
- W2152898032 hasConcept C179104552 @default.
- W2152898032 hasConcept C185592680 @default.
- W2152898032 hasConcept C193230392 @default.
- W2152898032 hasConcept C2776818218 @default.
- W2152898032 hasConcept C2777449187 @default.
- W2152898032 hasConcept C2778165595 @default.
- W2152898032 hasConcept C2780026642 @default.
- W2152898032 hasConcept C2780828025 @default.
- W2152898032 hasConcept C42219234 @default.
- W2152898032 hasConcept C71924100 @default.
- W2152898032 hasConceptScore W2152898032C100136789 @default.
- W2152898032 hasConceptScore W2152898032C120665830 @default.
- W2152898032 hasConceptScore W2152898032C121332964 @default.
- W2152898032 hasConceptScore W2152898032C126322002 @default.
- W2152898032 hasConceptScore W2152898032C179104552 @default.
- W2152898032 hasConceptScore W2152898032C185592680 @default.
- W2152898032 hasConceptScore W2152898032C193230392 @default.
- W2152898032 hasConceptScore W2152898032C2776818218 @default.
- W2152898032 hasConceptScore W2152898032C2777449187 @default.
- W2152898032 hasConceptScore W2152898032C2778165595 @default.
- W2152898032 hasConceptScore W2152898032C2780026642 @default.
- W2152898032 hasConceptScore W2152898032C2780828025 @default.
- W2152898032 hasConceptScore W2152898032C42219234 @default.