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- W2152904985 abstract "The in vitro cytotoxic activity of hexane, ethyl acetate and butanol extracts of the sea-cucumber Isostichopus badionotus (Holothuroidea) was tested against normal cells (Vero), human cervical carcinoma (HeLa) and breast adenocarcinoma (MCF-7 and MDA-MB-231) ATCC cells by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) assay. Hexane extracts from body walls and viscera showed high cytotoxic activity against HeLa cells (IC50’s = 48.5 and 42.5 µg mL-1, respectively), while the ethyl acetate extract of body walls was considered low active (IC50 = 98.3 μg mL-1). In addition, the body walls hexane extract showed a good selectivity index value of 12.0." @default.
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- W2152904985 date "2014-06-05" @default.
- W2152904985 modified "2023-10-04" @default.
- W2152904985 title "In Vitro Cytotoxic Activity of Isostichopus badionotus, a Sea Cucumber from Yucatan Peninsula Coast" @default.
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- W2152904985 doi "https://doi.org/10.6000/1927-5951.2014.04.03.3" @default.
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