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- W2152983030 abstract "Video-assisted thoracic surgery (VATS) lobectomy is an appealing alternative to open lobectomy via thoracotomy for non-small-cell lung cancer. However, there is no clear consensus in regard to the superior approach for long-term outcomes. The data are limited to small series, which precludes further clarification. Meta-analysis of these studies was performed in order to obtain a more objective determination of the oncological feasibility of VATS lobectomy. A systematic review of the PubMed and Embase databases was performed. Twenty observational studies reporting long-term outcomes were included, involving 2106 VATS and 2661 thoracotomy patients. There was an advantage in long-term mortality for patients who underwent VATS vs patients who underwent thoracotomy (meta difference in survival: 5%; 95% CI: 3–6%) with large heterogeneity among studies (Q = 42.6; P-value: 0.001; I2 = 55.7%). There was no evidence of publication bias. Compared with open lobectomy, VATS lobectomy appears to have improved long-term outcomes." @default.
- W2152983030 created "2016-06-24" @default.
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- W2152983030 creator A5026903916 @default.
- W2152983030 creator A5047330944 @default.
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- W2152983030 date "2013-02-14" @default.
- W2152983030 modified "2023-09-30" @default.
- W2152983030 title "Long-term survival in video-assisted thoracoscopic lobectomy vs open lobectomy in lung-cancer patients: a meta-analysis" @default.
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- W2152983030 doi "https://doi.org/10.1093/ejcts/ezt051" @default.
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