Matches in SemOpenAlex for { <https://semopenalex.org/work/W2153066069> ?p ?o ?g. }
- W2153066069 endingPage "1159" @default.
- W2153066069 startingPage "1151" @default.
- W2153066069 abstract "The neisserial porins are the major protein components of the outer membrane of the pathogenic Neisseria (N. meningitidis and N. gonorrhoeae). They have been shown to be able to enhance the immune response to poorly immunogenic substances (e.g., polysaccharides, peptides, glycolipids, etc.). To explore the basis of their potent adjuvant activity, the effect of the neisserial porins on T-B cell interactions and T cell costimulation was examined. Neisserial porins increased the surface expression of the costimulatory ligand B7-2 (CD86) but did not affect the expression of B7-1 (CD80). In addition, incubation with the neisserial porins increased the T lymphocyte costimulatory ability of B lymphocytes, which was inhibited by anti-B7-2 but not anti-B7-1 monoclonal antibodies. Upregulation of B7-2 on the surface of B lymphocytes may be the mechanism behind the immunopotentiating activity of neisserial porins." @default.
- W2153066069 created "2016-06-24" @default.
- W2153066069 creator A5035832852 @default.
- W2153066069 creator A5041770038 @default.
- W2153066069 creator A5069198313 @default.
- W2153066069 creator A5078739510 @default.
- W2153066069 date "1996-03-01" @default.
- W2153066069 modified "2023-09-27" @default.
- W2153066069 title "Neisserial porins induce B lymphocytes to express costimulatory B7-2 molecules and to proliferate." @default.
- W2153066069 cites W1497250343 @default.
- W2153066069 cites W1528906647 @default.
- W2153066069 cites W1549471106 @default.
- W2153066069 cites W1570594698 @default.
- W2153066069 cites W1600211602 @default.
- W2153066069 cites W1630899420 @default.
- W2153066069 cites W1734926275 @default.
- W2153066069 cites W1782106314 @default.
- W2153066069 cites W1806817428 @default.
- W2153066069 cites W1923005546 @default.
- W2153066069 cites W1967110222 @default.
- W2153066069 cites W1971659604 @default.
- W2153066069 cites W1978326037 @default.
- W2153066069 cites W1982878221 @default.
- W2153066069 cites W1984421836 @default.
- W2153066069 cites W1989914829 @default.
- W2153066069 cites W1991531286 @default.
- W2153066069 cites W1993814191 @default.
- W2153066069 cites W2001978111 @default.
- W2153066069 cites W2002861511 @default.
- W2153066069 cites W2003640920 @default.
- W2153066069 cites W2005265799 @default.
- W2153066069 cites W2007721356 @default.
- W2153066069 cites W2012241435 @default.
- W2153066069 cites W2017863958 @default.
- W2153066069 cites W2026512449 @default.
- W2153066069 cites W2029836713 @default.
- W2153066069 cites W2037852148 @default.
- W2153066069 cites W2044099387 @default.
- W2153066069 cites W2045654426 @default.
- W2153066069 cites W2052423192 @default.
- W2153066069 cites W2057167188 @default.
- W2153066069 cites W2062029576 @default.
- W2153066069 cites W2062994475 @default.
- W2153066069 cites W2064146006 @default.
- W2153066069 cites W2064861939 @default.
- W2153066069 cites W2069225782 @default.
- W2153066069 cites W2077301617 @default.
- W2153066069 cites W2082542602 @default.
- W2153066069 cites W2095642693 @default.
- W2153066069 cites W2100200230 @default.
- W2153066069 cites W2102152483 @default.
- W2153066069 cites W2102856388 @default.
- W2153066069 cites W2132252190 @default.
- W2153066069 cites W2133288457 @default.
- W2153066069 cites W2134822287 @default.
- W2153066069 cites W2144482901 @default.
- W2153066069 cites W2151225950 @default.
- W2153066069 cites W2151448684 @default.
- W2153066069 cites W2155229523 @default.
- W2153066069 cites W2164224564 @default.
- W2153066069 cites W2172173562 @default.
- W2153066069 cites W4205113006 @default.
- W2153066069 doi "https://doi.org/10.1084/jem.183.3.1151" @default.
- W2153066069 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2192323" @default.
- W2153066069 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8642257" @default.
- W2153066069 hasPublicationYear "1996" @default.
- W2153066069 type Work @default.
- W2153066069 sameAs 2153066069 @default.
- W2153066069 citedByCount "109" @default.
- W2153066069 countsByYear W21530660692012 @default.
- W2153066069 countsByYear W21530660692013 @default.
- W2153066069 countsByYear W21530660692014 @default.
- W2153066069 countsByYear W21530660692015 @default.
- W2153066069 countsByYear W21530660692016 @default.
- W2153066069 countsByYear W21530660692017 @default.
- W2153066069 countsByYear W21530660692018 @default.
- W2153066069 countsByYear W21530660692019 @default.
- W2153066069 countsByYear W21530660692022 @default.
- W2153066069 countsByYear W21530660692023 @default.
- W2153066069 crossrefType "journal-article" @default.
- W2153066069 hasAuthorship W2153066069A5035832852 @default.
- W2153066069 hasAuthorship W2153066069A5041770038 @default.
- W2153066069 hasAuthorship W2153066069A5069198313 @default.
- W2153066069 hasAuthorship W2153066069A5078739510 @default.
- W2153066069 hasBestOaLocation W21530660691 @default.
- W2153066069 hasConcept C104317684 @default.
- W2153066069 hasConcept C146587185 @default.
- W2153066069 hasConcept C147483822 @default.
- W2153066069 hasConcept C153911025 @default.
- W2153066069 hasConcept C159654299 @default.
- W2153066069 hasConcept C203014093 @default.
- W2153066069 hasConcept C22222904 @default.
- W2153066069 hasConcept C2776090121 @default.
- W2153066069 hasConcept C2781101188 @default.
- W2153066069 hasConcept C542903549 @default.
- W2153066069 hasConcept C547475151 @default.
- W2153066069 hasConcept C55493867 @default.
- W2153066069 hasConcept C86803240 @default.