FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2153090832> ?p ?o ?g. }

• W2153090832 endingPage "267" @default.
• W2153090832 startingPage "263" @default.
• W2153090832 abstract "Genotype 1b of hepatitis C virus (HCV) comprises mainly three subtypes, each named for its geographic prevalence (worldwide, W; Japan, J; and not in Japan, NJ).To characterise the newly identified subtypes of genotype 1b and to review factors associated with response to interferon (IFN) for each subtype.Chronic hepatitis patients (80 men and 41 women; mean age 48.5 years, range 20.7--69.3) with HCV genotype 1b (W type, n=41; J type, n=38) or genotype 2a (n=42) were treated according to the same IFN protocol. Forty four patients (36.4%) negative for serum HCV RNA six months after cessation of treatment were considered complete responders.Factors associated with complete response were investigated.Genotype 2a patients had lower viral loads (odds ratio 0.11 (95% confidence intervals (CI) 0.049--0.256)) and a better IFN response (odds ratio 0.25 (95% CI 0.117--0.552)) than genotype 1b patients whereas W type and J type patients had similar viral loads and responses to IFN. IFN response in W type patients was associated with female sex (odds ratio 0.23 (95% CI 0.055--0.983)) and low viral load (odds ratio 84.00 (95% CI 14.04--502.6)) whereas response in J type patients was related to transfusion history (odds ratio 7.20 (95% CI 1.443--35.91)), low viral load (odds ratio 117.0 (95% CI 17.82--768.3)), and genetic mutation in the interferon sensitivity determining region of the virus (odds ratio 0.08 (95% CI 0.013--0.553)). Multivariate analysis found low viral load (odds ratio 64.19 (95% CI 14.66--281.06)) to be the only significant independent factor associated with IFN response.Factors associated with IFN responsiveness in HCV infection differ with viral subtype." @default.
• W2153090832 created "2016-06-24" @default.
• W2153090832 creator A5026964230 @default.
• W2153090832 creator A5035683192 @default.
• W2153090832 creator A5037077435 @default.
• W2153090832 creator A5043762552 @default.
• W2153090832 creator A5064636550 @default.
• W2153090832 creator A5069896469 @default.
• W2153090832 creator A5081672689 @default.
• W2153090832 creator A5086287691 @default.
• W2153090832 date "2001-08-01" @default.
• W2153090832 modified "2023-09-25" @default.
• W2153090832 title "Interferon responsiveness in patients infected with hepatitis C virus 1b differs depending on viral subtype" @default.
• W2153090832 cites W115053149 @default.
• W2153090832 cites W1932676391 @default.
• W2153090832 cites W1974940736 @default.
• W2153090832 cites W1976110218 @default.
• W2153090832 cites W1987798475 @default.
• W2153090832 cites W1997368021 @default.
• W2153090832 cites W2006159079 @default.
• W2153090832 cites W2012002512 @default.
• W2153090832 cites W2017476113 @default.
• W2153090832 cites W2027252289 @default.
• W2153090832 cites W2027613773 @default.
• W2153090832 cites W2054442981 @default.
• W2153090832 cites W2061365719 @default.
• W2153090832 cites W2069633422 @default.
• W2153090832 cites W2072939892 @default.
• W2153090832 cites W2077968009 @default.
• W2153090832 cites W2079317094 @default.
• W2153090832 cites W2087924794 @default.
• W2153090832 cites W2095341026 @default.
• W2153090832 cites W2109145241 @default.
• W2153090832 cites W2115939918 @default.
• W2153090832 cites W2115956200 @default.
• W2153090832 cites W2118620804 @default.
• W2153090832 cites W2123384191 @default.
• W2153090832 cites W2132290252 @default.
• W2153090832 cites W2148838195 @default.
• W2153090832 cites W2152450239 @default.
• W2153090832 cites W2159954692 @default.
• W2153090832 cites W2162234181 @default.
• W2153090832 cites W2202972098 @default.
• W2153090832 cites W2335845212 @default.
• W2153090832 cites W2416508166 @default.
• W2153090832 cites W2416541929 @default.
• W2153090832 cites W2418578399 @default.
• W2153090832 cites W2466032891 @default.
• W2153090832 cites W4238397363 @default.
• W2153090832 cites W4241462015 @default.
• W2153090832 doi "https://doi.org/10.1136/gut.49.2.263" @default.
• W2153090832 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1728417" @default.
• W2153090832 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11454804" @default.
• W2153090832 hasPublicationYear "2001" @default.
• W2153090832 type Work @default.
• W2153090832 sameAs 2153090832 @default.
• W2153090832 citedByCount "13" @default.
• W2153090832 countsByYear W21530908322012 @default.
• W2153090832 crossrefType "journal-article" @default.
• W2153090832 hasAuthorship W2153090832A5026964230 @default.
• W2153090832 hasAuthorship W2153090832A5035683192 @default.
• W2153090832 hasAuthorship W2153090832A5037077435 @default.
• W2153090832 hasAuthorship W2153090832A5043762552 @default.
• W2153090832 hasAuthorship W2153090832A5064636550 @default.
• W2153090832 hasAuthorship W2153090832A5069896469 @default.
• W2153090832 hasAuthorship W2153090832A5081672689 @default.
• W2153090832 hasAuthorship W2153090832A5086287691 @default.
• W2153090832 hasBestOaLocation W21530908321 @default.
• W2153090832 hasConcept C104317684 @default.
• W2153090832 hasConcept C126322002 @default.
• W2153090832 hasConcept C135763542 @default.
• W2153090832 hasConcept C142462285 @default.
• W2153090832 hasConcept C156957248 @default.
• W2153090832 hasConcept C159047783 @default.
• W2153090832 hasConcept C203014093 @default.
• W2153090832 hasConcept C2522874641 @default.
• W2153090832 hasConcept C2776178377 @default.
• W2153090832 hasConcept C2776408679 @default.
• W2153090832 hasConcept C2909179924 @default.
• W2153090832 hasConcept C54355233 @default.
• W2153090832 hasConcept C71924100 @default.
• W2153090832 hasConcept C86803240 @default.
• W2153090832 hasConcept C90924648 @default.
• W2153090832 hasConceptScore W2153090832C104317684 @default.
• W2153090832 hasConceptScore W2153090832C126322002 @default.
• W2153090832 hasConceptScore W2153090832C135763542 @default.
• W2153090832 hasConceptScore W2153090832C142462285 @default.
• W2153090832 hasConceptScore W2153090832C156957248 @default.
• W2153090832 hasConceptScore W2153090832C159047783 @default.
• W2153090832 hasConceptScore W2153090832C203014093 @default.
• W2153090832 hasConceptScore W2153090832C2522874641 @default.
• W2153090832 hasConceptScore W2153090832C2776178377 @default.
• W2153090832 hasConceptScore W2153090832C2776408679 @default.
• W2153090832 hasConceptScore W2153090832C2909179924 @default.
• W2153090832 hasConceptScore W2153090832C54355233 @default.
• W2153090832 hasConceptScore W2153090832C71924100 @default.
• W2153090832 hasConceptScore W2153090832C86803240 @default.
• W2153090832 hasConceptScore W2153090832C90924648 @default.

• next