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- W2153152052 abstract "Recent studies have been reported that angiogenesis suppression may play a role in developing bisphosphonate-related osteonecrosis of the jaw (B-ONJ). According to these evidence we evaluated the role of VEGF as predictive marker of B-ONJ onset. Of the 81 patients, 6 developed B-ONJ following bisphosphonate treatment. These patients showed a strongest decrease in VEGF circulating levels at day 7 and at day 21 after the first administration. These data demonstrated for the first time that the anti-angiogenic properties of bisphosphonates are directly linked to B-ONJ pathogenesis and serum VEGF levels could represent an effective early predictive marker." @default.
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- W2153152052 date "2012-09-17" @default.
- W2153152052 modified "2023-10-14" @default.
- W2153152052 title "Serum VEGF levels as predictive marker of bisphosphonate-related osteonecrosis of the jaw" @default.
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- W2153152052 doi "https://doi.org/10.1186/1756-8722-5-56" @default.
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