Matches in SemOpenAlex for { <https://semopenalex.org/work/W2153156988> ?p ?o ?g. }
- W2153156988 endingPage "2904" @default.
- W2153156988 startingPage "2899" @default.
- W2153156988 abstract "The enteric nervous system (ENS) probably plays a dominant role in sheep scrapie pathogenesis, but little is known about the cell types involved. We investigated the ileal myenteric and submucosal plexuses of four naturally and four orally experimentally scrapie-affected ARQ/ARQ Sarda sheep, as well as those of 12 healthy-control Sarda sheep carrying different PrP genotypes. All scrapie-affected animals, euthanized at clinical-disease end stage, showed PrPd deposition within enteric glial cells (EGCs) and calbindin-immunoreactive (CALB-IR) and neuronal nitric oxide synthase (nNOS)-IR neurons. Whole-mount investigations revealed no significant differences between the densities of total, CALB-IR and nNOS-IR neurons in scrapie-affected versus healthy sheep, irrespective of PrP genotype. Our results suggest that EGCs and CALB-IR and nNOS-IR neurons are probably involved in the pathogenesis of natural and oral experimental sheep scrapie. Furthermore, the infectious agent may be less pathogenic towards ENS neurons than it is towards central nervous system neurons." @default.
- W2153156988 created "2016-06-24" @default.
- W2153156988 creator A5003688538 @default.
- W2153156988 creator A5015715237 @default.
- W2153156988 creator A5026438561 @default.
- W2153156988 creator A5049365616 @default.
- W2153156988 creator A5052089581 @default.
- W2153156988 creator A5053647201 @default.
- W2153156988 creator A5057518454 @default.
- W2153156988 creator A5059879236 @default.
- W2153156988 creator A5061967473 @default.
- W2153156988 creator A5067408184 @default.
- W2153156988 creator A5068647098 @default.
- W2153156988 creator A5074698855 @default.
- W2153156988 creator A5080047105 @default.
- W2153156988 creator A5085714590 @default.
- W2153156988 date "2007-10-01" @default.
- W2153156988 modified "2023-09-27" @default.
- W2153156988 title "Enteroglial and neuronal involvement without apparent neuron loss in ileal enteric nervous system plexuses from scrapie-affected sheep" @default.
- W2153156988 cites W1551003041 @default.
- W2153156988 cites W1645442091 @default.
- W2153156988 cites W1756014767 @default.
- W2153156988 cites W1920140446 @default.
- W2153156988 cites W1935439593 @default.
- W2153156988 cites W1977089582 @default.
- W2153156988 cites W1979001631 @default.
- W2153156988 cites W1985273834 @default.
- W2153156988 cites W1995227965 @default.
- W2153156988 cites W1998880294 @default.
- W2153156988 cites W2005676591 @default.
- W2153156988 cites W2012428814 @default.
- W2153156988 cites W2022822583 @default.
- W2153156988 cites W2027785700 @default.
- W2153156988 cites W2028877565 @default.
- W2153156988 cites W2031357490 @default.
- W2153156988 cites W2037800837 @default.
- W2153156988 cites W2038886416 @default.
- W2153156988 cites W2051338375 @default.
- W2153156988 cites W2070256863 @default.
- W2153156988 cites W2077656589 @default.
- W2153156988 cites W2081750840 @default.
- W2153156988 cites W2092472328 @default.
- W2153156988 cites W2093394063 @default.
- W2153156988 cites W2120130639 @default.
- W2153156988 cites W2122141418 @default.
- W2153156988 cites W2124577407 @default.
- W2153156988 cites W2125522501 @default.
- W2153156988 cites W2128667083 @default.
- W2153156988 cites W2141820674 @default.
- W2153156988 cites W2150497169 @default.
- W2153156988 cites W2154109443 @default.
- W2153156988 cites W2167842421 @default.
- W2153156988 cites W2324660492 @default.
- W2153156988 doi "https://doi.org/10.1099/vir.0.82907-0" @default.
- W2153156988 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17872545" @default.
- W2153156988 hasPublicationYear "2007" @default.
- W2153156988 type Work @default.
- W2153156988 sameAs 2153156988 @default.
- W2153156988 citedByCount "18" @default.
- W2153156988 countsByYear W21531569882012 @default.
- W2153156988 countsByYear W21531569882013 @default.
- W2153156988 countsByYear W21531569882014 @default.
- W2153156988 countsByYear W21531569882015 @default.
- W2153156988 countsByYear W21531569882021 @default.
- W2153156988 crossrefType "journal-article" @default.
- W2153156988 hasAuthorship W2153156988A5003688538 @default.
- W2153156988 hasAuthorship W2153156988A5015715237 @default.
- W2153156988 hasAuthorship W2153156988A5026438561 @default.
- W2153156988 hasAuthorship W2153156988A5049365616 @default.
- W2153156988 hasAuthorship W2153156988A5052089581 @default.
- W2153156988 hasAuthorship W2153156988A5053647201 @default.
- W2153156988 hasAuthorship W2153156988A5057518454 @default.
- W2153156988 hasAuthorship W2153156988A5059879236 @default.
- W2153156988 hasAuthorship W2153156988A5061967473 @default.
- W2153156988 hasAuthorship W2153156988A5067408184 @default.
- W2153156988 hasAuthorship W2153156988A5068647098 @default.
- W2153156988 hasAuthorship W2153156988A5074698855 @default.
- W2153156988 hasAuthorship W2153156988A5080047105 @default.
- W2153156988 hasAuthorship W2153156988A5085714590 @default.
- W2153156988 hasBestOaLocation W21531569881 @default.
- W2153156988 hasConcept C134018914 @default.
- W2153156988 hasConcept C142724271 @default.
- W2153156988 hasConcept C159047783 @default.
- W2153156988 hasConcept C169760540 @default.
- W2153156988 hasConcept C203014093 @default.
- W2153156988 hasConcept C204232928 @default.
- W2153156988 hasConcept C26265296 @default.
- W2153156988 hasConcept C2776735649 @default.
- W2153156988 hasConcept C2777439022 @default.
- W2153156988 hasConcept C2779134260 @default.
- W2153156988 hasConcept C2780942790 @default.
- W2153156988 hasConcept C3019804061 @default.
- W2153156988 hasConcept C529278444 @default.
- W2153156988 hasConcept C545706735 @default.
- W2153156988 hasConcept C71924100 @default.
- W2153156988 hasConcept C86803240 @default.
- W2153156988 hasConceptScore W2153156988C134018914 @default.
- W2153156988 hasConceptScore W2153156988C142724271 @default.