Matches in SemOpenAlex for { <https://semopenalex.org/work/W215320413> ?p ?o ?g. }
Showing items 1 to 89 of
89
with 100 items per page.
- W215320413 endingPage "8" @default.
- W215320413 startingPage "321" @default.
- W215320413 abstract "Urban public teaching and referral hospital in Espirito Santo, Brazil.To assess whether rates of infection and progression to active tuberculosis (TB) differed between household contacts of patients with multidrug-resistant (MDR) and drug susceptible (DS) pulmonary tuberculosis.Household contacts were assessed for evidence of TB infection and disease by purified protein derivative (PPD) skin testing, physical examination, chest X-ray, and sputum smear and culture.Among 133 close contacts of patients with MDR-TB, 44% were PPD-positive (> or =10 mm) compared to 37% of 231 contacts of the DS-TB cases (P = 0.18, chi2 test, OR 1.2, 95%CI 0.8-2). In a multivariate logistic regression analysis, after allowance for between-household variation in PPD responses, PPD positivity among household contacts of patients with MDR-TB remained comparable to PPD positivity in contacts of patients with DS-TB (OR 2.1, 95%CI 0.7-6.5). Respectively six (4%) and 11 (4%) contacts of the MDR- and DS-TB cases were found to have active TB at the time of initial evaluation or during follow-up (P = 0.78, chi2 test). Five of six contacts of MDR-TB cases and nine of nine contacts of DS-TB cases who developed TB, and for whom drug susceptibility test results were available, had the same bacterial susceptibility profiles as their index cases. DNA fingerprinting analysis of Mycobacterium tuberculosis isolates was identical between household contacts with active TB and the index MDR or DS-TB case for all 14 pairs compared.Our data suggest that the prevalence of tuberculous infection and progression to active TB among household contacts exposed to DS and MDR-TB cases is comparable, despite a longer duration of exposure of contacts to the index case in patients with MDR-TB." @default.
- W215320413 created "2016-06-24" @default.
- W215320413 creator A5003786049 @default.
- W215320413 creator A5007163828 @default.
- W215320413 creator A5031509414 @default.
- W215320413 creator A5041451458 @default.
- W215320413 creator A5060944225 @default.
- W215320413 creator A5068589038 @default.
- W215320413 creator A5069109715 @default.
- W215320413 creator A5069169873 @default.
- W215320413 creator A5091567283 @default.
- W215320413 creator A5079785549 @default.
- W215320413 date "2001-04-01" @default.
- W215320413 modified "2023-10-01" @default.
- W215320413 title "Infection and disease among household contacts of patients with multidrug-resistant tuberculosis." @default.
- W215320413 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11334250" @default.
- W215320413 hasPublicationYear "2001" @default.
- W215320413 type Work @default.
- W215320413 sameAs 215320413 @default.
- W215320413 citedByCount "69" @default.
- W215320413 countsByYear W2153204132012 @default.
- W215320413 countsByYear W2153204132013 @default.
- W215320413 countsByYear W2153204132014 @default.
- W215320413 countsByYear W2153204132015 @default.
- W215320413 countsByYear W2153204132016 @default.
- W215320413 countsByYear W2153204132017 @default.
- W215320413 countsByYear W2153204132018 @default.
- W215320413 countsByYear W2153204132019 @default.
- W215320413 countsByYear W2153204132020 @default.
- W215320413 countsByYear W2153204132022 @default.
- W215320413 countsByYear W2153204132023 @default.
- W215320413 crossrefType "journal-article" @default.
- W215320413 hasAuthorship W215320413A5003786049 @default.
- W215320413 hasAuthorship W215320413A5007163828 @default.
- W215320413 hasAuthorship W215320413A5031509414 @default.
- W215320413 hasAuthorship W215320413A5041451458 @default.
- W215320413 hasAuthorship W215320413A5060944225 @default.
- W215320413 hasAuthorship W215320413A5068589038 @default.
- W215320413 hasAuthorship W215320413A5069109715 @default.
- W215320413 hasAuthorship W215320413A5069169873 @default.
- W215320413 hasAuthorship W215320413A5079785549 @default.
- W215320413 hasAuthorship W215320413A5091567283 @default.
- W215320413 hasConcept C114851261 @default.
- W215320413 hasConcept C126322002 @default.
- W215320413 hasConcept C141071460 @default.
- W215320413 hasConcept C142724271 @default.
- W215320413 hasConcept C151956035 @default.
- W215320413 hasConcept C203014093 @default.
- W215320413 hasConcept C2776301714 @default.
- W215320413 hasConcept C2777975735 @default.
- W215320413 hasConcept C2779912665 @default.
- W215320413 hasConcept C2781069245 @default.
- W215320413 hasConcept C71924100 @default.
- W215320413 hasConcept C86803240 @default.
- W215320413 hasConcept C89423630 @default.
- W215320413 hasConceptScore W215320413C114851261 @default.
- W215320413 hasConceptScore W215320413C126322002 @default.
- W215320413 hasConceptScore W215320413C141071460 @default.
- W215320413 hasConceptScore W215320413C142724271 @default.
- W215320413 hasConceptScore W215320413C151956035 @default.
- W215320413 hasConceptScore W215320413C203014093 @default.
- W215320413 hasConceptScore W215320413C2776301714 @default.
- W215320413 hasConceptScore W215320413C2777975735 @default.
- W215320413 hasConceptScore W215320413C2779912665 @default.
- W215320413 hasConceptScore W215320413C2781069245 @default.
- W215320413 hasConceptScore W215320413C71924100 @default.
- W215320413 hasConceptScore W215320413C86803240 @default.
- W215320413 hasConceptScore W215320413C89423630 @default.
- W215320413 hasIssue "4" @default.
- W215320413 hasLocation W2153204131 @default.
- W215320413 hasOpenAccess W215320413 @default.
- W215320413 hasPrimaryLocation W2153204131 @default.
- W215320413 hasRelatedWork W1581555644 @default.
- W215320413 hasRelatedWork W1969111604 @default.
- W215320413 hasRelatedWork W2095123674 @default.
- W215320413 hasRelatedWork W2348488003 @default.
- W215320413 hasRelatedWork W2356275296 @default.
- W215320413 hasRelatedWork W2367214875 @default.
- W215320413 hasRelatedWork W2389178216 @default.
- W215320413 hasRelatedWork W2397467717 @default.
- W215320413 hasRelatedWork W4239562293 @default.
- W215320413 hasRelatedWork W4254242696 @default.
- W215320413 hasVolume "5" @default.
- W215320413 isParatext "false" @default.
- W215320413 isRetracted "false" @default.
- W215320413 magId "215320413" @default.
- W215320413 workType "article" @default.