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- W2153214512 abstract "The ubiquitin proteasome system (UPS) contributes to the pathophysiology of neurodegenerative diseases, and it is also a major determinant of synaptic protein degradation and activity. Recent studies in rodents and in the fruit fly Drosophila have shown that the activity of the UPS is involved in axonal degeneration. Increased knowledge of the UPS in synaptic and axonal reactions may provide novel drug targets for treatments of neuronal injuries and neurodegenerative disorders." @default.
- W2153214512 created "2016-06-24" @default.
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- W2153214512 date "2004-04-05" @default.
- W2153214512 modified "2023-09-30" @default.
- W2153214512 title "The ubiquitin proteasome system in synaptic and axonal degeneration" @default.
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- W2153214512 doi "https://doi.org/10.1083/jcb.200311091" @default.
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