Matches in SemOpenAlex for { <https://semopenalex.org/work/W2153215489> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W2153215489 endingPage "E951" @default.
- W2153215489 startingPage "E947" @default.
- W2153215489 abstract "Deletion analysis of the human growth hormone variant (GHV) promoter in transient transfection studies in BeWo choriocarcinoma and HepG2 cells indicated that the region extending from nt -158/+57 retained full transcriptional activity. DNase I footprint analysis of the fragment revealed a protected region at nt -82/-77, which is in a putative FOXF1/FOXF2 binding site. Supershift assays using an antiserum to human FOXF1 demonstrated that the protected region binds FOXF1. Overexpression of FOXF1 in BeWo and HepG2 cells induced the GHV promoter, whereas overexpression of FOXF2 was without effect. Mutagenesis of the FOXF1/FOXF2 site reduced basal promoter activity by 50-60% and markedly attenuated transactivation of the promoter by FOXF1. These studies indicate that FOXF1 induces GHV expression by interaction with a FOXF1/FOXF2 cis-element in the proximal promoter." @default.
- W2153215489 created "2016-06-24" @default.
- W2153215489 creator A5010005077 @default.
- W2153215489 creator A5018152535 @default.
- W2153215489 creator A5050843312 @default.
- W2153215489 date "2006-11-01" @default.
- W2153215489 modified "2023-09-25" @default.
- W2153215489 title "Transcription factor FOXF1 regulates growth hormone variant gene expression" @default.
- W2153215489 cites W1524354116 @default.
- W2153215489 cites W1752232811 @default.
- W2153215489 cites W1978094930 @default.
- W2153215489 cites W1985359667 @default.
- W2153215489 cites W1988086349 @default.
- W2153215489 cites W1993345547 @default.
- W2153215489 cites W1995221548 @default.
- W2153215489 cites W2010963920 @default.
- W2153215489 cites W2014757100 @default.
- W2153215489 cites W2030928772 @default.
- W2153215489 cites W2034038827 @default.
- W2153215489 cites W2037192406 @default.
- W2153215489 cites W2045797079 @default.
- W2153215489 cites W2053387942 @default.
- W2153215489 cites W2076376599 @default.
- W2153215489 cites W2094558613 @default.
- W2153215489 cites W2099130765 @default.
- W2153215489 cites W2113400357 @default.
- W2153215489 cites W2119468520 @default.
- W2153215489 cites W2136860888 @default.
- W2153215489 doi "https://doi.org/10.1152/ajpendo.00128.2006" @default.
- W2153215489 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16772323" @default.
- W2153215489 hasPublicationYear "2006" @default.
- W2153215489 type Work @default.
- W2153215489 sameAs 2153215489 @default.
- W2153215489 citedByCount "15" @default.
- W2153215489 countsByYear W21532154892012 @default.
- W2153215489 countsByYear W21532154892013 @default.
- W2153215489 countsByYear W21532154892014 @default.
- W2153215489 countsByYear W21532154892015 @default.
- W2153215489 countsByYear W21532154892016 @default.
- W2153215489 countsByYear W21532154892020 @default.
- W2153215489 countsByYear W21532154892023 @default.
- W2153215489 crossrefType "journal-article" @default.
- W2153215489 hasAuthorship W2153215489A5010005077 @default.
- W2153215489 hasAuthorship W2153215489A5018152535 @default.
- W2153215489 hasAuthorship W2153215489A5050843312 @default.
- W2153215489 hasConcept C101762097 @default.
- W2153215489 hasConcept C104317684 @default.
- W2153215489 hasConcept C1292079 @default.
- W2153215489 hasConcept C138885662 @default.
- W2153215489 hasConcept C143065580 @default.
- W2153215489 hasConcept C150194340 @default.
- W2153215489 hasConcept C153911025 @default.
- W2153215489 hasConcept C16318435 @default.
- W2153215489 hasConcept C179926584 @default.
- W2153215489 hasConcept C185592680 @default.
- W2153215489 hasConcept C41895202 @default.
- W2153215489 hasConcept C54009773 @default.
- W2153215489 hasConcept C55493867 @default.
- W2153215489 hasConcept C86339819 @default.
- W2153215489 hasConcept C86803240 @default.
- W2153215489 hasConceptScore W2153215489C101762097 @default.
- W2153215489 hasConceptScore W2153215489C104317684 @default.
- W2153215489 hasConceptScore W2153215489C1292079 @default.
- W2153215489 hasConceptScore W2153215489C138885662 @default.
- W2153215489 hasConceptScore W2153215489C143065580 @default.
- W2153215489 hasConceptScore W2153215489C150194340 @default.
- W2153215489 hasConceptScore W2153215489C153911025 @default.
- W2153215489 hasConceptScore W2153215489C16318435 @default.
- W2153215489 hasConceptScore W2153215489C179926584 @default.
- W2153215489 hasConceptScore W2153215489C185592680 @default.
- W2153215489 hasConceptScore W2153215489C41895202 @default.
- W2153215489 hasConceptScore W2153215489C54009773 @default.
- W2153215489 hasConceptScore W2153215489C55493867 @default.
- W2153215489 hasConceptScore W2153215489C86339819 @default.
- W2153215489 hasConceptScore W2153215489C86803240 @default.
- W2153215489 hasIssue "5" @default.
- W2153215489 hasLocation W21532154891 @default.
- W2153215489 hasLocation W21532154892 @default.
- W2153215489 hasOpenAccess W2153215489 @default.
- W2153215489 hasPrimaryLocation W21532154891 @default.
- W2153215489 hasRelatedWork W2009464217 @default.
- W2153215489 hasRelatedWork W2009966535 @default.
- W2153215489 hasRelatedWork W2062687382 @default.
- W2153215489 hasRelatedWork W2068890039 @default.
- W2153215489 hasRelatedWork W2078113843 @default.
- W2153215489 hasRelatedWork W2095454319 @default.
- W2153215489 hasRelatedWork W2134013614 @default.
- W2153215489 hasRelatedWork W2363432561 @default.
- W2153215489 hasRelatedWork W2506115081 @default.
- W2153215489 hasRelatedWork W4307449862 @default.
- W2153215489 hasVolume "291" @default.
- W2153215489 isParatext "false" @default.
- W2153215489 isRetracted "false" @default.
- W2153215489 magId "2153215489" @default.
- W2153215489 workType "article" @default.