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- W2153253704 abstract "On Feb 13, 2003, a 76-year-old woman was referred with a follicular variant of a thyroid papillary carcinoma and underwent a total thyroidectomy and debulking of the right laterocervical region, which showed several metastases in the right laterocervical lymph nodes, vessel infiltration, and a neoplastic thrombosis of the internal jugular vein (pathological stage T4bN1aMx). During the next 2 years, apart from the persistence of the disease in the upper mediastinum and right laterocervical lymph nodes, the rapid and progressive appearance of multiple lung and bone metastases was noted during whole-body scans with recombinant thyroid-stimulating hormone (TSH)-stimulated iodine-131. She therefore underwent another surgical debulking of the right laterocervical region and upper mediastinum, and excision of the right internal jugular vein with the neoplastic thrombus on July 29, 2003, with external-beam radiotherapy (50 Gy in 28 fractions) of the laterocervical region and upper mediastinum in November, 2003, and three applications of recombinant TSH-stimulated 131I metabolic treatment (4834 MBq on June 6, 2003; 7400 MBq on Feb 23, 2004; and 5374 MBq on Nov 15, 2004). However, these treatments had little effect on disease progression, as shown by persistence of the disease in the upper mediastinum and right laterocervical lymph nodes in the first 131I whole-body scan after treatment, followed rapidly by multiple bone and lung metastases seen in the second and third scans after treatment." @default.
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- W2153253704 date "2006-10-01" @default.
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- W2153253704 title "Cell differentiation and iodine-131 uptake in poorly differentiated thyroid tumour in response to nevirapine" @default.
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- W2153253704 doi "https://doi.org/10.1016/s1470-2045(06)70908-1" @default.
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