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- W2153313132 abstract "Results: The total serum cholesterol levels were significantly lower (P < 0.05) although serum HDL levels were significantly higher (P < 0.01) in all EGs. Total serum lipid levels were higher in EG-15 and EG-20 groups than in CGs. The structural degenerations in the perikaryon and neuropil were found prominent in EG15 and EG-20 groups but not in EG-10. Marked damage in the neuronal and neuropilic structure was observed in rats who received long–term high doses of vitamin B6. Based on these results, a relationship between cerebral cortex damage and serum total lipid and HDL levels in the EG-15 and EG-20 groups is suggested. Conclusions: Dietary excess of vitamin B6 intake reduces serum total cholesterol levels, but not serum HDL and total lipid levels, and also causes cerebral cortex damage in long-term treatment. Thus, a careful diet plan and monitoring of vitamin B6 dose are recommended in patients who are supplemented with this vitamin." @default.
- W2153313132 created "2016-06-24" @default.
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- W2153313132 date "2006-06-01" @default.
- W2153313132 modified "2023-09-26" @default.
- W2153313132 title "Effects of Excess Vitamin B6 Intake on Serum Lipid Profile and Cerebral Cortex in Rats" @default.
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