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- W2153455246 abstract "Arterial stiffness is increased in type 1 diabetes (T1D), before any clinical complications of the disease are evident. The aim of the present paper was to investigate the association between cardiac autonomic function and arterial stiffness in a cohort of young T1D patients, without history of hypertension and any evidence of macrovascular and/or renal disease. Large artery stiffness was assessed by measurement of carotid-femoral pulse wave velocity (PWV). Cardiac autonomic function was assessed by the cardiovascular tests proposed by Ewing and Clarke. Patients with a high cardiac autonomic neuropathy score (4) had significantly higher PWV than those with a low score (0-1). A negative, heart rate-independent, correlation between PWV and heart rate variation during respiration was observed (). In multivariable analysis, index was the strongest correlate of PWV ( β -coefficient = −0.326, ). Cardiac parasympathetic function is a strong predictor of large arterial stiffness, in young T1D patients free of macrovascular and renal complications." @default.
- W2153455246 created "2016-06-24" @default.
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- W2153455246 date "2011-01-01" @default.
- W2153455246 modified "2023-09-27" @default.
- W2153455246 title "Cardiac Autonomic Function Correlates with Arterial Stiffness in the Early Stage of Type 1 Diabetes" @default.
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- W2153455246 doi "https://doi.org/10.1155/2011/957901" @default.
- W2153455246 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3143454" @default.
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